Three teams of Hughes researchers are closer to understanding how axons, the long projections of nerve cells, grow toward and across an organism's midline to wire up both sides of the body.
HHMI researchers have determined the three-dimensional structure of a protein-RNA complex that shepherds the production of infectious copies of HIV. The structure is a promising target for new antiviral drugs. Article published in the January 16, 1998 issue of Science.
Researchers suspect that a combination of genes and environment determine one's susceptibility to allergic conditions. Hughes researchers and colleagues at Washington University have identified a mutant protein that may cause hypersensitivity to common allergens.
HHMI physician postdoctoral fellow Michael Yaffe and his colleagues have demonstrated a new mechanism that governs chaperone activity and affects the vitality of cells.
HHMI predoctoral fellow develops a computer program that offers a quick, easy and free way to produce restriction maps of DNA sequences.
Benjamin Doranz, an HHMI predoctoral fellow, is helping to devise a gene therapy technique that could destroy the hidden, latent reservoir of HIV-infected cells that escape drug therapy. Article published in the November 21 issue of Science.
HHMI international scholar B. Brett Finlay hopes to learn exactly how E. coli adheres to target cells - and to improve the treatment of diarrheal diseases.
New centers at medical schools provide centralized access to the increasingly powerful tools and specialized expertise that drive modern biology.
HHMI's representative in Russia, Laura Kennedy, has helped the Institute's international research scholars in the region to overcome a wide range of problems.
Research by an undergraduate at the University of South Carolina could lead to a better understanding of the genetic relationship among dinosaurs, birds and alligators.
Hanna H. Gray, president emeritus and Harry Pratt Judson Distinguished Service Professor of History of the University of Chicago, has been elected chairman of the Trustees of the Howard Hughes Medical Institute, effective November 4.
Lisa Goodrich and HHMI investigator Matthew Scott are probing how genes that guide normal development can sometimes go awry and lead to cancer.
Stephen M. Cohen has been elected vice president and chief financial officer of the Howard Hughes Medical Institute by its Trustee, it was announced today by Purnell W. Choppin, M.D., president of the Institute.
More and more institutions are sending undergraduates off campus - to industry, a government laboratory, another college or university - to do research.
Two Hughes investigators, working in parallel, advance our understanding of AIDS by discovering the way HIV, the virus that causes AIDS, penetrates a cell.
Hughes researcher Yuet Wai Kan and his colleagues have designed a prenatal blood test to diagnose fetuses at risk for developing sickle cell anemia and thalassemias.