A gene crucial to C. elegans mating behavior resembles a gene involved in polycystic kidney disease.
HHMI investigators say that stem cells may prove to be better than viruses for delivering corrective genes to tissues throughout the body.
HHMI investigators have found a gene that determines whether roundworms prefer to eat alone or in a group. Further studies may give a glimpse at the genetic origins of social behavior.
HHMI researchers are making fundamental advances in understanding how genes control the shape and spatial orientation of organs.
Scientists have uncovered a critical mechanism by which light resets the biological clock in flies. This finding could lead to new treatments for jet lag and improved therapies for mood and sleep disorders.
HHMI researchers have used a fragment of HIV to deliver proteins into the cells of living mice.
Two related proteins that act as brakes for a variety of cellular growth processes appear to play a critical role in ensuring that both blood cells and immune system cells are neither overactive nor overabundant.
HHMI researchers believe their technique can be used to determine the function of all of the fruit fly's genes.
HHMI researchers have found the first hereditary human sleep disorder that is caused by a single gene. The disorder is passed from generation to generation in the same simple pattern characteristic of traits such as eye color.
A team of biologists has determined the three-dimensional structure of an enzyme that allows certain bacteria to resist the killing effects of the antibiotic gentamicin. The structure is also shared by a number of proteins involved in basic biological processes, including circadian rhythms and gene regulation.
A genetic mutation common in the most severe forms of muscular dystrophy also predisposes to heart damage.
Two genes that generate the immune system's remarkable diversity are controlled by the same small piece of DNA.
Mice born without a gene that regulates appetite exhibit unexpected attacks of narcolepsy.
A two-tiered boost to the immune system may allow the body to better fight cancer on its own.
New theories about how neural activity and visual stimuli sculpt the developing visual system.
A newly discovered protein in nerve cells holds enzymes poised for action next to their receptor.
Interferon cures only 20 percent of patients infected with hepatitis C virus. HHMI researchers may know the reason why.
Complex mathematical analysis reveals how potassium is allowed to travel across the cell membrane.
Sons conceived with the aid of a popular in vitro fertilization technique carry same genetic mutations that rendered their fathers infertile.
Molecular studies of a family of genes are pruning branches from the old evolutionary tree.
Genetic studies confirm that one gene mutation plays a major role in inherited deafness; the importance of another genetic mutation is called into question.
HHMI researchers discover a gene responsible for triggering embryonic cells in the inner ear to develop into sound- and motion-sensing hair cells.
HHMI researchers have found a protein whose activity controls the shape of a developing organ.
HHMI researchers have discovered a molecule that resembles a component of snake toxins, but has a dramatically different effect on the nervous system.
Research to improve vaccines for infectious diseases must move forward. At the same time, according to HHMI investigator Barry Bloom, scientists should be perfecting vaccines that tackle pathogens associated with other diseases, such as cancer and heart disease.