Lung cancer cells hijack a master cellular signal and use it to seed deadly new tumors in the brain, bone marrow, and other organs.
New evidence suggests that damage to nerve cells in people with MS accumulates because the body's mechanism for repairing the nerve coating called myelin stalls out.
Researchers have identified two proteins that begin to explain how radically slashing calories leads to a longer life.
Joan Massagué honored for elucidating one of the fundamental processes that control cell division.
A new method will speed the identification of the targets of microRNAs—the tiny but powerful bits of nucleic acid that tweak gene expression to influence many aspects of health and human disease.
HHMI is expanding collaborations with the Jane Coffin Childs Memorial Fund, the Helen Hay Whitney Foundation, the Damon Runyon Cancer Research Foundation, and the Life Sciences Research Foundation to increase support for outstanding postdoctoral researchers.
New research shows that a father’s sperm passes along a previously unrecognized set of instructions that helps guide the early development of his children.
A new molecular portrait of rotavirus may help researchers design more effective vaccines against the lethal gastrointestinal infection that kills 500,000 children annually.
A new microscopy technique is enabling researchers to capture videos of fast-moving cellular processes with super high resolution.
New research indicates that in most cases, natural selection may shape the human genome much more slowly than previously thought.
HHMI researchers identify many potential new drug targets for cancers long deemed "untouchable."
Research suggests new avenues to treat or prevent infections by parasitic worms.
A protein often accused of sparking autoimmune disease can suppress the onset of inflammatory bowel disease.
HHMI scientists have taken a major step towards understanding the molecular mechanisms that transform Listeria monocytogenes from a harmless soil-dweller to a dangerous human pathogen by mapping the genes that Listeria expresses under different environmental conditions.
Horvitz's election to the Fellowship of the Royal Society recognizes his exceptional contributions to science.
Ultraviolet radiation from the sun can zap DNA, damage cells, and set the stage for the subsequent development of cancer. Scientists have now identified the built-in safety mechanism that forces some cells damaged by UV radiation to commit suicide so they do not perpetuate harmful mutations.
La radiación ultravioleta del sol puede destruir el ADN, dañar las células y predisponer al organismo para el desarrollo subsecuente de cáncer. Unos científicos han identificado el mecanismo de seguridad intrínseco que fuerza a algunas células dañadas por la radiación UV a cometer suicidio para no perpetuar mutaciones dañinas.
The movement of blood through the aorta of a developing embryo triggers the production of new blood stem cells.
Scientists have identified a protein that hampers learning and memory by keeping DNA inside neurons tightly coiled.
Genetic clues suggest how invasive breast cancer cells pry their way into the tightly protected interior of the brain.
With the emergence of a new strain of influenza A(H1N1), scientists have a unique opportunity to study viral evolution in action.
The pulsing of a single neuron can switch a brain’s waves from the equivalent of a big ocean swell to ripples on a pond.
La pulsación de una sola neurona puede cambiar las ondas cerebrales de forma equivalente a lo que sería transformar las ondas del oleaje marino en las pequeñas ondas que se pueden observar en una laguna.
A new strategy for generating plug-and-play components could make life easier for synthetic biologists.