A protein that is already the target of experimental drugs that aim to extend life is now known to play a key role in learning and memory.
An ambitious new analysis in mice demonstrates that for more than 1,300 genes active in the brain, there is a significant bias as to which copy is active—the one inherited from the mother or the one that came from the father.
Researchers have identified signaling pathways by which the normal prion protein switches on the general protein synthesis necessary to promote the growth and development of brain cells.
A new imaging method will allow researchers to study speedy cell processes over hours and days rather than seconds, and to examine how morphological defects arise in developing animals.
Five teams will compete in the final round of an international scientific challenge designed to speed development of new computational tools to accurately and automatically reconstruct the shape of brain cells.
Babies delivered via Cesarean section harbor a different ecosystem of bacteria than babies born vaginally.
Jumping genes, thought to have settled down over millions of years of evolution, may be an ongoing source of genetic variation between individuals.
The mucosal immune system is often the first to tangle with microbial invaders. To better understand it, scientists should focus on the interplay between the mucosal immune system and friendly microbes.
Researchers have identified a set of hybrid genes that may accelerate the growth of prostate cancer, gastric cancer, and melanoma.
The prestigious $500,000 Lemelson-MIT Prize honors outstanding mid-career inventors dedicated to improving the world through technological invention and innovation.
A pediatric kidney cancer called Wilms tumor may, with just a few genetic changes, hijack pathways that ordinarily drive development of normal kidney tissue.
HHMI researcher Thomas C. Sudhof shares the 2010 Kavli Prize in Neuroscience with Richard H. Scheller and James E. Rothman.
A new genetic analysis suggests that the strains of influenza circulating in the United States can migrate to the rest of the world.
A mysterious swallowing disorder bears similarities to a disease that afflicts parrots and other exotic birds.
A genome-wide search reveals a genetic survival pathway that is switched on in many of the most aggressive glioblastomas.
A unique analysis of environmental contributors to type 2 diabetes has confirmed a link between several pollutants and the disease, while also pointing toward a form of vitamin E as a possible risk factor.
A groundbreaking comparison of human and Neandertal genomes reveals astonishingly few differences in the DNA that codes for proteins.
Scientists have new clues about what makes some people's immune systems better equipped to control HIV.
In a new study investigating just how pervasive a fruit fly’s sexual identity actually is, researchers find that most cells in flies’ bodies are identical, regardless of whether they are in a male or a female.
El parásito intestinal Giardia lamblia cambia de vestimenta casi tan frecuentemente como una modelo en una pasarela parisina, pero su amplio guardarropa de proteínas superficiales podría en realidad ser su propia perdición. Parásitos Giardia diseñados para que expresen todas sus proteínas de superficie se comportaron como vacunas que podrían ayudar a prevenir o a atenuar futuras infecciones intestinales.
A Giardia parasite engineered to express its extensive wardrobe of surface proteins worked as a vaccine that could help prevent or mitigate future intestinal infections.
By switching off a single gene, researchers have created mice that behave much like people with obsessive-compulsive disorder. The animal model could help scientists design new therapies for the debilitating condition.
Some bacteria take over cells by interfering with an important process called SUMOylation, which helps cells respond to stress.
On May 26, Egnor will give a free public lecture titled, "Whistling in the Dark: What Can Mouse Vocalizations Tell Us about the Brain?"
Scientists have uncovered thousands of DNA segments that were missing from the reference sequence of the human genome.