Health officials have held off from recommending an inexpensive malaria drug for widespread use because of concerns about drug resistance. New research drawn from 10 years of field and laboratory studies suggests the drug may be a safe and effective way to prevent malaria.
HHMI researchers develop tiny life-support packets for therapeutic cells.
A cooperative online game has attracted 50,000 players whose “distributed thinking” has, in some cases, proven more powerful than computers in predicting the structure of proteins.
A type of prostate cell that has been largely ignored by cancer researchers can trigger malignant prostate cancer.
Janelia Farm researchers show it takes steady hands to measure the brain activity of a fruit fly while it is walking.
HHMI researchers discover that induced pluripotent stem cells retain a genetic memory of their tissue of origin.
A protein that is already the target of experimental drugs that aim to extend life is now known to play a key role in learning and memory.
An ambitious new analysis in mice demonstrates that for more than 1,300 genes active in the brain, there is a significant bias as to which copy is active—the one inherited from the mother or the one that came from the father.
Researchers have identified signaling pathways by which the normal prion protein switches on the general protein synthesis necessary to promote the growth and development of brain cells.
A new imaging method will allow researchers to study speedy cell processes over hours and days rather than seconds, and to examine how morphological defects arise in developing animals.
Five teams will compete in the final round of an international scientific challenge designed to speed development of new computational tools to accurately and automatically reconstruct the shape of brain cells.
Babies delivered via Cesarean section harbor a different ecosystem of bacteria than babies born vaginally.
Jumping genes, thought to have settled down over millions of years of evolution, may be an ongoing source of genetic variation between individuals.
The mucosal immune system is often the first to tangle with microbial invaders. To better understand it, scientists should focus on the interplay between the mucosal immune system and friendly microbes.
Researchers have identified a set of hybrid genes that may accelerate the growth of prostate cancer, gastric cancer, and melanoma.
The prestigious $500,000 Lemelson-MIT Prize honors outstanding mid-career inventors dedicated to improving the world through technological invention and innovation.
A pediatric kidney cancer called Wilms tumor may, with just a few genetic changes, hijack pathways that ordinarily drive development of normal kidney tissue.
HHMI researcher Thomas C. Sudhof shares the 2010 Kavli Prize in Neuroscience with Richard H. Scheller and James E. Rothman.
A new genetic analysis suggests that the strains of influenza circulating in the United States can migrate to the rest of the world.
A mysterious swallowing disorder bears similarities to a disease that afflicts parrots and other exotic birds.
A genome-wide search reveals a genetic survival pathway that is switched on in many of the most aggressive glioblastomas.
A unique analysis of environmental contributors to type 2 diabetes has confirmed a link between several pollutants and the disease, while also pointing toward a form of vitamin E as a possible risk factor.
A groundbreaking comparison of human and Neandertal genomes reveals astonishingly few differences in the DNA that codes for proteins.
Scientists have new clues about what makes some people's immune systems better equipped to control HIV.
In a new study investigating just how pervasive a fruit fly’s sexual identity actually is, researchers find that most cells in flies’ bodies are identical, regardless of whether they are in a male or a female.