Safe and effective vaccines could complement efforts to treat those already infected with cholera and provide clean water and sanitation to control its spread.
A new study has pinned some of the symptoms of Rett syndrome to a set of neurons that usually work to rein in nerve cell firing in the brain.
New research suggests rising temperatures in the highlands of East Africa are at least partly to blame for the increase in malaria transmission in recent decades.
A previously overlooked group of cells has been shown to be essential in helping adult stem cells multiply and revitalize damaged tissue.
Through an international study of the genome in persons who control HIV without the need for medications, scientists have identified a handful of amino acids that seem to predict a person’s ability to successfully keep the virus in check.
Researchers have shown that radiation-resistance among tumor stem cells can be dramatically lowered by heating them up.
A new analysis of gene duplication across the human genome reveals far more variation in gene copy number than anticipated.
Research in mice suggests that manipulating a single molecule might help eliminate fears that have been etched into memory.
A new study reveals that many pancreatic tumors take nearly 20 years to become lethal after the first genetic perturbations appear, suggesting an opportunity for early diagnosis.
A pair of international research scholars has discovered a deep connection between the circadian clocks of plants and animals.
Dos becarios internacionales de investigación descubren una profunda conexión entre el reloj circadiano de plantas y animales: un gen que está involucrado en la creación de formas alternativas de proteínas relacionadas con el ritmo circadiano.
Susan Lindquist, an HHMI investigator, and Stephen Benkovic, a member of HHMI's Scientific Review Board, are among ten recipients of this year's National Medal of Science.
Cellular clocks throughout the body are precisely synchronized by tiny fluctuations in body temperature.
Laboratory studies of planarians' reproductive cycles suggest new strategies for treating infections that affect hundreds of millions worldwide.
Four HHMI investigators, an HHMI early career scientist, and a senior fellow at Janelia Farm have been elected to the IOM.
The discovery of an odd couple of genes that team up to trigger rare and difficult-to-detect gastrointestinal stromal tumors could eventually lead to better diagnostics and treatments.
Researchers are inching their way toward a new HIV vaccine strategy by studying the cells of people who have naturally strong immune defenses against the virus.
HHMI and the Gordon and Betty Moore Foundation announce a new partnership to support some of the nation's most innovative plant scientists.
Jeffrey Friedman and Douglas Coleman are being honored for discoveries that led to the identification of leptin, a hormone that regulates appetite and body weight.
Mutations that supercharge a cellular garbage disposal may explain why cancer cells can thrive even as their genetic material multiplies out of control.
A targeted search combined with today's rapid DNA sequencing technology leads researchers to a genetic culprit for a rare disease.
Researchers have new details of how an enzyme helps bacteria slice up foreign genetic material.
Most of the clear cell ovarian carcinoma samples examined in a new study carried a gene mutation that alters the epigenetics of cells.
HHMI researchers have found that malaria parasites can produce multiple versions of a protein that causes infected blood cells to grab onto the inner wall of blood vessels.
Multiple jury prizes were awarded in recognition of contributions advancing technology to automate an important but tedious component of neuroscience research.