New research pinpoints differences between cancer stem cells in squamous cell cancer and normal stem cells in the skin, which could be exploited to create powerful new anti-cancer therapeutics.
A new study helps explain how fruit flies commit details of their surroundings to memory.
Medzhitov shares Shaw Prize for discoveries related to innate immunity.
Joanne Chory and Thomas Steitz have been elected foreign members of the Fellowship of the Royal Society.
A detailed comparison of DNA and RNA in human cells has uncovered a surprising number of cases where the corresponding sequences are not, as has long been assumed, identical.
HHMI scientists suggest that as many as 20 percent of sporadic autism cases can be explained by spontaneous gene mutations.
Científicos del HHMI sugieren que tanto como un 20 por ciento de los casos de autismo esporádico pueden explicarse por mutaciones genéticas espontáneas.
A class of proteins known for its involvement in muscle development, brain connectivity, and cancer has now been found in the liver, where it spurs sugar production when we need it most.
Adult planarians, masters of regeneration, harbor pluripotent stem cells that appear to have the same all-purpose qualities as embryonic stem cells.
The same signaling pathway can both cause and suppress disease in blood cells.
Six HHMI investigators are among the 72 new members and 18 foreign associates elected today.
With a new animal model of angle-closure glaucoma, researchers have pinpointed a gene that may be to blame.
Human cytomegalovirus hijacks an antiviral protein and uses it to enhance infection by slowing down the host cell’s energy production.
Janelia Farm group leader Mats Gustafsson was a leader in the field of structured illumination light microscopy.
Eight Howard Hughes Medical Institute investigators are among those newly elected to the academy.
New data about what drives aortic aneurysm progression in Marfan syndrome will help guide treatment decisions and inform efforts to develop new therapies.
At any given moment, a few neurons are ready to take charge of the next piece of information to be stored in the brain's hippocampus.
The biological basis of schizophrenia is not fully understood, but new research by HHMI international research scholar Michael Salter offers insights into the disruptions in brain chemistry that underlie the debilitating mental illness.
Using chemical genetics to single out a single kinase among the hundreds inside a cell, scientists have gleaned new information about how one such protein might contribute to cancer-promoting signaling.
New maps detailing where certain markers of genetic regulation are found in a variety of cell types will help researchers interpret large-scale analyses.
A zebrafish model of human melanoma has helped scientists identify new targets for potential therapies.
New research offers a genetic explanation for why some patients' lung tumors disappear almost completely when treated with the drug erlotinib, while other patients' responses are far less dramatic.
Searching for a new food source is a big decision for a worm, based on hunger, dining companions, oxygen availability, and, according to a new study, genetics.
The 2011 prize honors Elaine Fuchs, James Thomson, and Shinya Yamanaka for pioneering work in isolating human stem cells.
Flickering black and white movies show components of the spliceosome coming and going from bits of RNA as they await processing.