A new technique transforms biological tissue into an optically transparent sample that retains its original structure and molecular information.
Stephen Elledge recognized for research on DNA repair.
New research reveals how a localized source of a signaling molecule directs a dividing stem cell to produce two different cells—one identical to its parent, the other a more specialized cell type—and aligns those cells.
Researchers have found that temperatures on the surface of the tropical South Atlantic Ocean in July can predict the severity of malaria outbreaks in northwestern India that begin to peak four months later.
Scientists have a new view of the cellular machinery that assembles directly on DNA and readies it for transcription into RNA, the first step in protein production.
Three HHMI scientists are among 11 honored for excellence in research aimed at curing intractable diseases and extending human life.
Scientists have discovered that periodic ring-shaped actin arrangements encircle the long axonal fibers of nerve cells, in contrast to the linear meshworks that typically give cells their shapes.
HHMI scientists discover how a single molecule in a living cell can respond differently to different strengths of an external signal.
A new analysis suggests that the regulatory protein MeCP2 works with the modified nucleotide 5hmC to facilitate gene activation in the brain.
Scientists have discovered the molecular pathway responsible for detecting loose bits of DNA outside a cell’s nucleus and setting off an immune reaction.
Rather than scrutinizing hours of video, scientists can quickly teach the software how to recognize key behaviors.
AAAS recognizes Ulrike Heberlein and Nelson Spruston for meritorious efforts to advance science.
A new DNA sequencing technique has enabled researchers to map for the first time the influential chemical modifications known as methylation marks throughout the genome of a pathogenic bacterium.
eLife makes first collection of research articles available online.
Robert Lefkowitz de HHMI comparte el premio con Brian Kobilka por estudios sobre los receptores acoplados a proteínas G.
Only a few animals, such as songbirds, whales, and dolphins, are known to be vocal learners, modifying the sequence or pitch of their sounds based on what they hear from other members of their species. New evidence suggests mice can be added to that list.
HHMI's Robert Lefkowitz shares prize with Brian Kobilka for research on G-protein coupled receptors.
HHMI and the University of KwaZulu-Natal open new research institute in Durban, South Africa.
In experiments with rats, researchers found that the rejection of an old belief correlates with abrupt changes in activity in a region of the brain involved in cognitive functions such as reward anticipation and decision-making.
HHMI selects 13 of the world’s leading basic science researchers to receive Senior International Research Scholar (SIRS) awards. The awards support outstanding biomedical scientists working outside the United States who have made significant contributions to fundamental research in the biological sciences.
HHMI investigator Ronald D. Vale of UCSF will share the 2012 Albert Lasker Basic Medical Research Award.
Thousands of genes in organs throughout the body show predictable daily fluctuations. New research reveals complexity in how those genes' cycles of activity are controlled.
A discovery of how ethylene triggers changes in gene activity could lead to new ways to stop or slow ripening.
The vaccinia virus increases the size of its genome when it confronts the immune system, thereby increasing the odds of a random mutation that will improve its survival.