HHMI scientists are making 'chemical factories' that help laboratory animals produce resveratrol -- the compound behind red wine's frequently touted health benefits.
Scientists can turn on or block regeneration in zebrafish with the flip of a molecular switch.
Researchers have learned how the immune system slices and dices genes so B cells can program antibodies to seek out and destroy invaders.
Two HHMI research teams have discovered new information about how the botulinum neurotoxin shuts down neurons with deadly efficiency.
HHMI researchers discover a line of communication that helps hair follicles organize and align themselves into a well ordered pattern.
Scientists discover a new place to search for the factors that cause neurons to sprout connections.
After five years, some 95 percent of study participants have survived the cancer due to treatment with Gleevec.
P[acman], a new tool for inserting large genes into precise locations on the chromosome, may enable researchers to overcome challenges in pinning down the function of genes.
New research shows that at least 10 percent of genes in the human population can vary in the number of copies of DNA sequences they contain—a finding that alters current thinking that the DNA of any two humans is 99.9 percent identical in content and identity.
Nuevo estudio muestra que al menos el 10 por ciento de los genes de la población humana puede tener un número distinto de copias de secuencias de ADN –descubrimiento que modifica la idea actual de que el ADN de dos seres humanos cualesquiera es un 99.9 por ciento similar en contenido e identidad–.
New findings hint that dendritic spines could make the human brain a far more efficient learning machine than that of other animals.
Analyzing the machinery a roundworm uses to repress genes on an entire chromosome reveals surprising principles about gene regulation.
Here is a list of research institutions that qualify for the 2007 competition.
Brief summaries of the research carried out by the 12 patient-oriented researchers selected by HHMI in 2002
HHMI announces new national competition to appoint outstanding physician-scientists as HHMI investigators. The Institute expects to select approximately 15 new researchers by Fall 2007 and is committing approximately $200 million to their first term of appointment.
Researchers have created a map of the protein landscape that regulates a stem cell's ability to differentiate into multiple types of mature cells.
HHMI researchers and their colleagues developed a systematic method for speeding up the crystallization of proteins, an advance that may greatly aid x-ray crystallography.
A new study suggests that human evolution was not just a matter of spontaneous advantageous mutations arising within the human lineage.
HHMI researchers have created a map that helps explain how the brain generates the assortment of specialized proteins it needs to process information.
A newly identified gene mutation helps explain a subset of cases of osteogenesis imperfecta.
By turning on a single gene, researchers can prevent skin stem cells from maturing into the three types of adult skin cells.
Now that clinical trials have shown ranibizumab's "miraculous" effects on patients' eyesight, a crucial next step is to compare ranibizumab to a related drug, which is less than ten times the cost.
HHMI investigator Craig Mello of the University of Massachusetts Medical School and Stanford researcher Andrew Fire honored for discovery of RNA interference.
El investigador del HHMI Craig C. Mello, de la Facultad de Medicina de la Universidad de Massachussets, y el investigador de Stanford, Andrew Fire, fueron honrados por el descubrimiento de la interferencia de ARN.
A structural protein can determine whether an insect develops the highly organized, light-harvesting eye of a fly.