Janelia scientists have borrowed a technique from the field of astronomy to overcome biology’s equivalent of the twinkling of stars and the shimmering mirages in desert landscapes.
A small but aggressive fraction of metastatic cancer cells can re-infiltrate the original tumor, boosting its malignant potential.
Una fracción pequeña pero agresiva de células cancerígenas puede reinfiltrar el tumor original, aumentando su potencial maligno.
From the brain's point of view, not every itch is the same. HHMI researchers have identified a new type of itch receptor.
In a tour-de-force of evolutionary sleuthing, researchers have traced a yellow-to-black color change in African fruit flies to five single-letter genetic mutations.
Researchers have identified a naturally occurring human protein that helps prevent infection by H1N1 influenza and other viruses, including West Nile and dengue virus.
A newly identified gene mutation is one of only a handful of mutations outside the X chromosome to be linked to intellectual disability.
A new method for strengthening proteins could lead to improved laundry soap, better nanotechnology, and less expensive cancer drugs.
Comparing the DNA of fish with and without spiny pelvic hindfins provides evidence that evolution can leap rather than shuffle.
Using advanced electron-microscopy and modeling techniques, a team of researchers has determined the structure of a eukaryotic ribosome with unprecedented accuracy.
Scientists have discovered a new type of stem cell in the skin that acts surprisingly like certain stem cells found in embryos: both can generate fat, bone, cartilage, and even nerve cells. These newly-described dermal stem cells may one day prove useful for treating neurological disorders and persistent wounds, such as diabetic ulcers.
HHMI researchers have identified a new factor necessary for the development of medulloblastomas, the most common type of malignant childhood brain cancer.
A protein found in the saliva of ticks may prove to be an attractive target for a new type of Lyme disease vaccine.
Scientists have found that preeclampsia can dramatically increase the likelihood that a woman will experience low thyroid function later in life.
Researchers have developed a new imaging method to track how a person’s brain divides up duties between the two halves.
A new imaging tool lets researchers watch individual neurons in the brains of living animals light up as they work together to control the animal’s behavior.
Scientists have an ambitious new strategy for untangling the evolutionary history of humans and their biological relatives: obtain, preserve, and sequence the DNA of approximately one species for each genus of living mammals, birds, reptiles, amphibians, and fish.
Variations from DNA's iconic double-helix shape transmit information about where proteins need to bind to make sure the right genes are activated or silenced during development.
New research shows that histones that escape from cells aren’t just a byproduct of sepsis, they’re a ringleader in its development.
Cutting down the amount of fat particles in cells may be an effective way to prevent the dengue fever virus from replicating and spreading.
Nueva investigación muestra que el reducir la cantidad de partículas grasas de las células podría ser una forma eficaz de evitar que el virus de la fiebre del dengue se replique y disemine.
A signaling pathway that guides the early development of animals from flies to humans also helps a regenerating flatworm orient itself from head to tail.
José A. Rodriguez, estudiante doctoral financiado por el HHMI en la Universidad de California en Los Ángeles y un equipo multidisciplinario de colegas han encontrado que el parásito Trypanasoma brucei, que causa la enfermedad africana del sueño, no se mueve en sólo una dirección como un sacacorchos.
New research by an HHMI-funded graduate students and his colleagues has overturned an 150-year-old idea of how the parasite Trypanasoma brucei moves. T. brucei causes African sleeping sickness.
Por primera vez, científicos han diagnosticado una enfermedad genética secuenciando completamente todos los genes de un paciente.