Kaelin is one of five scientists honored with the 2010 Canada Gairdner International Award in recognition of their contributions to medical science.
New research reveals how genetic and environmental factors influence an organ that has not traditionally taken much of the blame for diabetes and cardiovascular disease.
Researchers have identified key cells involved in zebrafish heart regeneration and begun to decipher the instructions the cells use to carry out their work.
New studies of how the heart develops in mouse embryos have brought researchers closer to understanding how to induce the body’s own cells to rebuild damaged arteries.
Scientists have found several new ways to kill M. tuberculosis, which could lead to the development of alternative drugs.
An ambitious survey has identified differences in the binding of master regulators called transcription factors that affect how genes are expressed in different people.
In a discovery that may one day aid law enforcement in identifying suspects, researchers have found that skin bacteria left behind on keyboards and computer mice can identify the objects’ users.
A new software package promises to greatly speed up scientists’ ability to assemble and manipulate extremely detailed microscope images.
Experiments with an artificial cell surface demonstrate that a tumor’s aggressiveness is strongly correlated to its mechanical pulling power.
New findings about an often fatal neurodegenerative disease suggest that helping a beneficial protein linger a little longer could promote neuron survival.
Researchers have discovered how one New World hemorrhagic fever virus latches onto and infects human cells, offering a much-needed lead toward new treatments.
Las fiebres hemorrágicas del Nuevo Mundo son enfermedades infecciosas emergentes que se encuentran en Sudamérica y que pueden causar síntomas terribles, similares a los del Ébola. Investigadores del HHMI han descubierto exactamente cómo un virus de fiebre hemorrágica del Nuevo Mundo se adhiere e infecta a las células humanas, lo que ofrece una pista muy necesaria para lograr nuevos tratamientos.
Jean-Philippe Vielle-Calzada, becario internacional de investigación del Instituto Médico Howard Hughes (HHMI), se preguntó si podría aprender lo suficiente sobre la genética de la reproducción asexual para aplicarla a las plantas que se producen sexualmente.
An HHMI scientist has moved a step closer to turning sexually-reproducing plants into asexual reproducers, a finding that could have profound implications for agriculture.
Endothelial cells keep blood stem cells dividing healthily in a lab dish much longer and more effectively than previous methods of growing the cells.
A new study suggests that gut microbes might one day be grouped along with inadequate exercise and overeating as a cause of obesity and metabolic syndrome.
The mitochondrial genome, long thought to be nearly identical in every cell in the human body, actually varies to a surprising degree.
At the AAAS Annual Meeting, David Anderson discussed how studies of model organisms such as mice and fruit flies can improve scientists' understanding of the neural basis of emotion.
At the AAAS Annual Meeting on Feb. 20, Owen Witte discussed a new tool to understand how cancers grow—and with it a new opportunity to identify novel cancer drugs.
At the AAAS Annual Meeting on Feb. 20, George Daley described the current climate facing stem cell researchers in the United States.
Researchers have created a group of stem cells from patients who have a disorder that causes accelerated aging and bone marrow failure. Using a genetic reprogramming technique to “turn back the molecular clock” in these cells appears to reset the cells and reverses rapid aging.
A new vaccine tested in 100 West African children triggers the immune system to produce antibodies against the malaria parasite at levels normally seen only in adults who have strong resistance to the disease.
Una nueva vacuna que se probó en 100 niños de África Occidental hizo que el sistema inmune produjera anticuerpos contra el parásito de la malaria en niveles que normalmente sólo se observan en adultos que tienen una fuerte resistencia a la enfermedad.
With a collection of tools for rapidly processing changing visual cues, the eyes and brain work together to create meaningful images from raw signals.
Researchers have found the key factors that cause proteins to turn into sticky, fibrous clumps that can grind cellular activity to a halt.