In the region of the brain that controls motor planning, a self-reinforcing loop of neuronal signaling helps establish connectivity during early development.
Researchers have uncovered the enzyme that transfers phosphate to milk proteins like casein, but also to proteins found in bones and teeth enamel.
Dixon, who has led HHMI's scientific programs since 2007, will retire from the Institute in summer 2013.
Fourteen HHMI scientists are among 84 newly elected members.
Bonnie Bassler and Jack Dixon are among eight newly elected foreign members.
Nine HHMI investigators and one HHMI Professor are elected to the American Academy of Arts and Sciences.
The May 9th lecture, Shining Light on How the Brain Works, is free, but tickets are required for admission.
Many of the most severe mutations identified in patients with autism affected proteins that work together in one large interconnected network.
As fish in different parts of the world adapted to live in fresh water, the same sites in the genome were changed time and again.
HHMI researchers Thomas M. Jessell and Michael Rosbash honored for significant contributions to medical science.
HHMI seeks to appoint up to 30 new HHMI investigators in 2013. Applications open on March 15, 2012.
Long, ropy fibers were long thought to be the causes of these diseases including Alzheimer's and Parkinsons, but research over the past decade has revealed that fibers arent amyloid proteins' most toxic form.
In a mouse model of Alzheimer’s disease, an overactive enzyme causes memory problems by shutting off genes related to neuronal communication.
The Gilliam program aims to increase the diversity of college and university faculty by supporting future scientific leaders during their graduate studies.
Defectos en el gen que codifica para la proteína más grande del cuerpo humano son responsables de más casos de la enfermedad que los causados por todas las otras mutaciones conocidas.
Defects in the gene that encodes the human body’s largest protein are responsible for more cases of dilated cardiomyopathy than are caused by all other known mutations associated with the heart disorder.
HHMI researcher and colleagues design and develop drug that prolongs survival in men with advanced prostate cancer.
Investigador del HHMI y sus colegas diseñan y desarrollan una droga que prolonga la supervivencia de hombres con cáncer de próstata avanzado.
HHMI investigator Brian Druker honored for role in developing new cancer drug.
Meet the 2012 International Early Career Scientists
Top biomedical scientists from 12 countries will receive an important boost at a critical time in their careers from HHMI’s inaugural International Early Career Scientist awards.
Perlmutter's lecture on “Building Better Medicines: Drug Discovery in the 21st Century” will take place on February 15.
A breakdown of cellular junk may explain how exercise fends off metabolic disorders and protects against other diseases.
Researchers have discovered a molecular master switch that triggers the genetic overhaul plants need to fight off pathogens.
The gene mutation that causes retinoblastoma changes the way cells turn on and off many other genes.