Howard Hughes Medical Institute (HHMI) scientists have created a portrait of a DNA-snipping protein called Cas9, a powerful research tool used in many labs for genome editing.
In the last five years, 4,800 students at 73 colleges and universities nationwide have taken HHMI's Science Education Alliance (SEA) Phage Hunters Advancing Genomics and Evolutionary Science (PHAGES) research course.
New research from HHMI scientists reveals how a foreign-DNA-destroying system, known as CRISPR, efficiently locates its DNA targets within a bacterial genome.
By studying which genes modern humans still retain from our Neanderthal ancestors, researchers are able to tell a clearer story about the biological impact of human-Neanderthal interbreeding.
In his "Dialogues of Discovery" talk at Janelia on February 26, 2014, HHMI investigator Jeremy Nathans will explore the diverse ways in which color vision has evolved.
HHMI seeks to appoint up to 25 new biomedical researchers through a national open competition.
Janelia neurobiologist Igor Siwanowicz wins first prize in the 2013 Olympus BioScape Digital Imaging Competition with a photo that shows the gaping trap of an aquatic carnivorous plant, humped bladderwort about to consume microinvertebrates.
HHMI investigator is among 6 honored for excellence in research aimed at curing intractable diseases and extending human life.
HHMI researchers identify a potential Achilles heel in the oncogene K-Ras.
A new technique developed by Janelia researchers allows scientists to use electron beams to determine protein structure from tiny crystals.
The Howard Hughes Medical Institute (HHMI) is adding four new films to its award-winning catalog of short science documentaries for the classroom.
Ulrike Heberlein, a scientific program director and laboratory head at the Janelia Farm Research Campus, will deliver a public lecture at Janelia titled, “Alcoholism: 100 Million Years in the Making?”
New evidence suggests that aneuploidy patterns of chromosome deletion or amplification that are recurrent among tumors actually represent a driving force during tumor evolution and are very frequent in cancer.
HHMI researchers have discovered that the pool of inactive HIV viruses that lingers silently in a patient’s body is larger than expected. The viruses continue to be a threat because they retain the ability to become active even after treatment with the best HIV drugs.
Six HHMI scientists have been elected to membership in the Institute of Medicine.
HHMI researchers have developed a mouse model of scleroderma. Their studies have uncovered some of the molecular pathways that go awry to cause the disease.
Neurons deep in the fly’s brain tune in to some of the same basic visual features that neurons in bigger animals such as humans pick out in their surroundings. The new research is an important milestone toward understanding how the fly brain extracts relevant information about a visual scene to guide behavior.
HHMI researchers have designed an inhibitor that can reduce the expression of the mutated gene that causes hypertrophic cardiomyopathy, a potentially fatal heart condition.
La Real Academia de las Ciencias Sueca anunció que los investigadores del HHMI, Randy W. Schekman y Thomas C. Südhof, y James E. Rothman de la Universidad de Yale son los ganadores del Premio Nobel de Fisiología o Medicina 2013 por sus descubrimientos sobre la maquinaria que regula el tráfico de vesículas, un importante sistema de transporte de nuestras células.
The Nobel Assembly at the Karolinska Institute announced that HHMI investigators Randy W. Schekman and Thomas C. Südhof, and Yale's James E. Rothman are the recipients of the 2013 Nobel Prize in Physiology or Medicine for their discoveries of machinery regulating vesicle traffic, a major transport system in our cells.
Janelia scientists launch collaboration to develop a new generation of devices to detect neural activity.
Some breast cancer cells have a leg up on survival—the genes they express make them more likely to spread and prosper in bone tissue.
Scientists have discovered that an active ingredient in an over-the-counter skin cream slows or stops the effects of Parkinson’s disease on brain cells.
Neuroscientist Cori Bargmann will discuss "Ancient Molecules and the Modern Brain: Understanding our Social Nature," at Janelia on September 18.