Soon, each UC Santa Barbara student will get a taste of doing original research on the roundworm Caenorhabditis elegans, a widely used genetic model.
The Go Teach program is designed to improve the quality of tomorrow’s K–12 science teachers by recruiting prospective teachers from the ranks of undergraduate science students.
A new dual-mentorship program offers students the opportunity to learn from two faculty collaborators from different disciplines—most often a basic scientist and a translational scientist— and how to apply scientific understanding to a practical problem in human health.
With the help of an HHMI grant, Harvard revamped its introductory science curriculum to expose students to a set of interdisciplinary foundation courses.
Dartmouth College envisions a course that integrates the quantitative and mathematical aspects of chemistry into the study of biological processes, such as those that would be presented in an introductory cell biology course.
SUNY at Stony Brook's Research Fellows Program focuses on students from economically disadvantaged backgrounds or from groups that are traditionally underrepresented in the sciences.
William and Mary will use part of its new $1.2 million grant to spread the enthusiasm for authentic research to more students.
Virginia Tech is developing a “Scieneering” minor that will unite life sciences with engineering.
With the help of an HHMI grant, the biology faculty is designing a program called FASTRAC—FAcilitating STudent Research ACcess—that will identify up to 20 community college students each year who are interested in working in a research lab after they transfer to UC Davis.
As part of a $1.4 million HHMI science education grant, 5 to 10 LSU undergraduates will travel to the labs of infectious disease researchers in Europe, Africa, South America, and Asia in the hopes of broadening their perspective and introduce them to new ways of thinking about science.
With the help of a new $1.6 million grant from HHMI, Iowa State University will revamp its introductory lab courses and develop a new interdisciplinary class on science and sustainability so that sophomores can experience firsthand how science can help solve complex and socially important problems.
A groundbreaking comparison of human and Neandertal genomes reveals astonishingly few differences in the DNA that codes for proteins.
Scientists have new clues about what makes some people's immune systems better equipped to control HIV.
In a new study investigating just how pervasive a fruit fly’s sexual identity actually is, researchers find that most cells in flies’ bodies are identical, regardless of whether they are in a male or a female.
Professors from three schools participating in HHMI's Science Education Alliance will help create the next generation of research-based courses to extend the program’s reach to upperclassmen.
Jack Dixon and Gregory Petsko are elected to the oldest learned society in the United States.
Eleven HHMI investigators and one Janelia Farm senior fellow have been elected to the National Academy of Sciences.
El parásito intestinal Giardia lamblia cambia de vestimenta casi tan frecuentemente como una modelo en una pasarela parisina, pero su amplio guardarropa de proteínas superficiales podría en realidad ser su propia perdición. Parásitos Giardia diseñados para que expresen todas sus proteínas de superficie se comportaron como vacunas que podrían ayudar a prevenir o a atenuar futuras infecciones intestinales.
A Giardia parasite engineered to express its extensive wardrobe of surface proteins worked as a vaccine that could help prevent or mitigate future intestinal infections.
By switching off a single gene, researchers have created mice that behave much like people with obsessive-compulsive disorder. The animal model could help scientists design new therapies for the debilitating condition.
Some bacteria take over cells by interfering with an important process called SUMOylation, which helps cells respond to stress.
On May 26, Egnor will give a free public lecture titled, "Whistling in the Dark: What Can Mouse Vocalizations Tell Us about the Brain?"
Scientists have uncovered thousands of DNA segments that were missing from the reference sequence of the human genome.
A molecule best known for fighting off cellular clutter is now recognized as an important defender against another cellular threat: viruses.
New research provides details of how genetic mismanagement by RNA can lead to a human disease—in this case, breast cancer.
New research suggests that training to do a new task causes groups of brain cells to “learn” how to work together more efficiently.
Jibrell joins HHMI from the Ford Foundation in New York where he served as chief technology officer.
A new discovery shows how wing spots evolved in a species of polka-dotted fruit fly, and underscores the concept that evolution likes to tinker with existing genetic machinery.
Sean Carroll, an award-winning scientist, author, and educator, will become the Institute’s vice president for science education.
Kaelin is one of five scientists honored with the 2010 Canada Gairdner International Award in recognition of their contributions to medical science.
A statement regarding fraudulent activity involving checks that are purported to be from HHMI.
New research reveals how genetic and environmental factors influence an organ that has not traditionally taken much of the blame for diabetes and cardiovascular disease.
Researchers have identified key cells involved in zebrafish heart regeneration and begun to decipher the instructions the cells use to carry out their work.
Fred R. Lummis, a Houston businessman and entrepreneur, has been elected a Trustee of the Howard Hughes Medical Institute.
New studies of how the heart develops in mouse embryos have brought researchers closer to understanding how to induce the body’s own cells to rebuild damaged arteries.
Scientists have found several new ways to kill M. tuberculosis, which could lead to the development of alternative drugs.
Over the past year, two scientists who have been at Janelia since its opening took on new roles as group leaders, and six new fellows were recruited to head their own research groups.
An ambitious survey has identified differences in the binding of master regulators called transcription factors that affect how genes are expressed in different people.
In a discovery that may one day aid law enforcement in identifying suspects, researchers have found that skin bacteria left behind on keyboards and computer mice can identify the objects’ users.
A new software package promises to greatly speed up scientists’ ability to assemble and manipulate extremely detailed microscope images.
Experiments with an artificial cell surface demonstrate that a tumor’s aggressiveness is strongly correlated to its mechanical pulling power.
HHMI has selected five exceptional individuals to receive the 2010 Gilliam Fellowships. These students will join a dynamic group of 30 Gilliam fellows, who share a passion for science and a commitment to increasing diversity in the sciences.
New findings about an often fatal neurodegenerative disease suggest that helping a beneficial protein linger a little longer could promote neuron survival.
Five students have been named 2010 Gilliam Fellows.
Silvia N. Kariuki is a 2010 Gilliam Fellow.
Lisandro Maya-Ramos is a 2010 Gilliam Fellow.
Mariam El-Ashmawy is a 2010 Gilliam Fellow.
Flavian D. Brown is a 2010 Gilliam Fellow.
Rachel A. Johnston is a 2010 Gilliam Fellow.
Researchers have discovered how one New World hemorrhagic fever virus latches onto and infects human cells, offering a much-needed lead toward new treatments.
Las fiebres hemorrágicas del Nuevo Mundo son enfermedades infecciosas emergentes que se encuentran en Sudamérica y que pueden causar síntomas terribles, similares a los del Ébola. Investigadores del HHMI han descubierto exactamente cómo un virus de fiebre hemorrágica del Nuevo Mundo se adhiere e infecta a las células humanas, lo que ofrece una pista muy necesaria para lograr nuevos tratamientos.
Jean-Philippe Vielle-Calzada, becario internacional de investigación del Instituto Médico Howard Hughes (HHMI), se preguntó si podría aprender lo suficiente sobre la genética de la reproducción asexual para aplicarla a las plantas que se producen sexualmente.
An HHMI scientist has moved a step closer to turning sexually-reproducing plants into asexual reproducers, a finding that could have profound implications for agriculture.
Endothelial cells keep blood stem cells dividing healthily in a lab dish much longer and more effectively than previous methods of growing the cells.
A new study suggests that gut microbes might one day be grouped along with inadequate exercise and overeating as a cause of obesity and metabolic syndrome.
The mitochondrial genome, long thought to be nearly identical in every cell in the human body, actually varies to a surprising degree.
At the AAAS Annual Meeting, David Anderson discussed how studies of model organisms such as mice and fruit flies can improve scientists' understanding of the neural basis of emotion.
At the AAAS Annual Meeting on Feb. 20, Owen Witte discussed a new tool to understand how cancers grow—and with it a new opportunity to identify novel cancer drugs.
At the AAAS Annual Meeting on Feb. 20, George Daley described the current climate facing stem cell researchers in the United States.
In their report "Scientific Foundations for Future Physicians"—discussed Feb. 19 at the AAAS Annual Meeting—the AAMC and HHMI challenge colleges and universities to seize the opportunity to make premedical and medical education more interactive and interdisciplinary.
Researchers have created a group of stem cells from patients who have a disorder that causes accelerated aging and bone marrow failure. Using a genetic reprogramming technique to “turn back the molecular clock” in these cells appears to reset the cells and reverses rapid aging.
A new vaccine tested in 100 West African children triggers the immune system to produce antibodies against the malaria parasite at levels normally seen only in adults who have strong resistance to the disease.
Una nueva vacuna que se probó en 100 niños de África Occidental hizo que el sistema inmune produjera anticuerpos contra el parásito de la malaria en niveles que normalmente sólo se observan en adultos que tienen una fuerte resistencia a la enfermedad.
With a collection of tools for rapidly processing changing visual cues, the eyes and brain work together to create meaningful images from raw signals.
Researchers have found the key factors that cause proteins to turn into sticky, fibrous clumps that can grind cellular activity to a halt.
Two groups of HHMI scientists working independently have identified a critical enzyme that allows a malaria-causing parasite to take over and thrive in human red blood cells.
Dos grupos de científicos del HHMI que trabajaban de forma independiente han identificado una enzima crítica que permite que el parásito que causa la malaria controle los glóbulos rojos sanguíneos humanos y prospere en el interior de los mismos.
Researchers have discovered that when DNA-copying machines run head-on into oncoming traffic, they kick the obstacles out of their way.
The BBVA Foundation honors HHMI investigator Robert Lefkowitz for research on G protein-coupled receptors.
With the discovery of a sodium taste receptor, researchers have now identified the molecular receptors, cells, and coding logic for all five basic tastes.
HHMI researchers have developed a new method for growing human liver cells outside the body, which may boost efforts to develop a vaccine or treatment for hepatitis C infection.
Researchers have devised a new method that increases the number of blood vessel-forming cells they can make from human embryonic stem cells.
Investigadores han demostrado que distintas mutaciones que causan cáncer en células vecinas pueden cooperar para producir tumores.
Researchers have shown that distinct cancer-causing mutations in neighboring cells can cooperate to produce tumors.
Researchers have new information about how proteins called Argonautes bind to small RNAs and selectively shut down protein production.
Scientists have identified the genetic cause of a rare eye movement disorder and found that specific mutations in the disease gene can cause additional errors in neurodevelopment and neuronal survival.
A newly identified enzyme could help scientists create stem cells and arrest the growth of cancers by giving them the ability to wipe clean cells' developmental slates.
Terrible and swift as anthrax appears to its victims, the deadly toxin takes its time breaking into their cells. The entry of anthrax toxin into its cellular target is part of a carefully-planned, two-pronged attack, scientists have found.
Gerald M. Rubin, director of the Howard Hughes Medical Institute’s Janelia Farm Research Campus, will deliver a public lecture titled “The Fly Brain and Yours—Closer Than You Think,” at Janelia Farm in Ashburn, VA.
Janelia scientists have borrowed a technique from the field of astronomy to overcome biology’s equivalent of the twinkling of stars and the shimmering mirages in desert landscapes.
A small but aggressive fraction of metastatic cancer cells can re-infiltrate the original tumor, boosting its malignant potential.
Una fracción pequeña pero agresiva de células cancerígenas puede reinfiltrar el tumor original, aumentando su potencial maligno.
From the brain's point of view, not every itch is the same. HHMI researchers have identified a new type of itch receptor.
Bruns, who has led the HHMI Grants Program since 2001, will retire in August 2010.
HHMI Professor Catherine Drennan infused her introductory chemistry class with examples from biology and medicine in an attempt to help her students make connections between disciplines.
In a tour-de-force of evolutionary sleuthing, researchers have traced a yellow-to-black color change in African fruit flies to five single-letter genetic mutations.
Researchers have identified a naturally occurring human protein that helps prevent infection by H1N1 influenza and other viruses, including West Nile and dengue virus.
HHMI has invited 12 more schools to join the Science Education Alliance to engage their students in scientific discovery on a national scale.
A newly identified gene mutation is one of only a handful of mutations outside the X chromosome to be linked to intellectual disability.
A new method for strengthening proteins could lead to improved laundry soap, better nanotechnology, and less expensive cancer drugs.
Comparing the DNA of fish with and without spiny pelvic hindfins provides evidence that evolution can leap rather than shuffle.
Using advanced electron-microscopy and modeling techniques, a team of researchers has determined the structure of a eukaryotic ribosome with unprecedented accuracy.
Scientists have discovered a new type of stem cell in the skin that acts surprisingly like certain stem cells found in embryos: both can generate fat, bone, cartilage, and even nerve cells. These newly-described dermal stem cells may one day prove useful for treating neurological disorders and persistent wounds, such as diabetic ulcers.
HHMI researchers have identified a new factor necessary for the development of medulloblastomas, the most common type of malignant childhood brain cancer.
A protein found in the saliva of ticks may prove to be an attractive target for a new type of Lyme disease vaccine.
Scientists have found that preeclampsia can dramatically increase the likelihood that a woman will experience low thyroid function later in life.
The Howard Hughes Medical Institute is offering grants to 23 schools that are developing new graduate programs or enhancing existing programs that prepare scientists to translate laboratory discoveries into new medical treatments and diagnostics.
The Howard Hughes Medical Institute is awarding a total of $16 million to 23 schools that are developing graduate programs to prepare scientists to translate laboratory discoveries into new medical treatments and diagnostics.
Researchers have developed a new imaging method to track how a person’s brain divides up duties between the two halves.
A new imaging tool lets researchers watch individual neurons in the brains of living animals light up as they work together to control the animal’s behavior.