HHMI international scholar B. Brett Finlay hopes to learn exactly how E. coli adheres to target cells - and to improve the treatment of diarrheal diseases.
New centers at medical schools provide centralized access to the increasingly powerful tools and specialized expertise that drive modern biology.
HHMI's representative in Russia, Laura Kennedy, has helped the Institute's international research scholars in the region to overcome a wide range of problems.
Research by an undergraduate at the University of South Carolina could lead to a better understanding of the genetic relationship among dinosaurs, birds and alligators.
Hanna H. Gray, president emeritus and Harry Pratt Judson Distinguished Service Professor of History of the University of Chicago, has been elected chairman of the Trustees of the Howard Hughes Medical Institute, effective November 4.
Lisa Goodrich and HHMI investigator Matthew Scott are probing how genes that guide normal development can sometimes go awry and lead to cancer.
Stephen M. Cohen has been elected vice president and chief financial officer of the Howard Hughes Medical Institute by its Trustee, it was announced today by Purnell W. Choppin, M.D., president of the Institute.
More and more institutions are sending undergraduates off campus - to industry, a government laboratory, another college or university - to do research.
Two Hughes investigators, working in parallel, advance our understanding of AIDS by discovering the way HIV, the virus that causes AIDS, penetrates a cell.
Hughes researcher Yuet Wai Kan and his colleagues have designed a prenatal blood test to diagnose fetuses at risk for developing sickle cell anemia and thalassemias.
Doug Wright has left behind the construction business to study stem cells and search for new techniques to improve the success of bone marrow transplants.
Hyock Joo Kwon has helped to determine the structure of the active site of bacteriophage lambda integrase, a well-studied protein that had proven difficult to visualize.
The Howard Hughes Medical Institute today announced that is has awarded $15 million in grants to support the research of 47 outstanding biomedical researchers in Argentina, Brazil, Canada, Chile, Mexico and Venezuela.
A talk by Argentine scientist Ana Belen Elgoyhen highlights the problems faced by many biomedical researchers in Latin America.
The College of the Holy Cross offers free training every summer to two fortunate Worcester Public School science teachers.
High school science teachers are refreshing their skills at summer programs offered by the College of the Holy Cross, the University of Missouri-Columbia, and the Woodrow Wilson National Fellowship Foundation.
The University of Missouri-Columbia is bringing state-of-the-art equipment to teachers who might not otherwise have such exposure.
While filling in for public school teachers who are away on sabbatical, some recent science graduates from the College of the Holy Cross discover that teaching is their calling.
Teacher training programs give scientists new understanding and respect for their precollege colleagues.
Stephen Blacklow, a former HHMI postdoctoral fellow, has made a discovery that may explain why some people have high cholesterol levels
Jeffrey M. Friedman and colleagues report that the weight-reducing effects of the hormone leptin result from interaction with a receptor in the brain's hypothalamus and other tissues.
New Jersey State Aquarium runs a day camp and other programs where Camden youngsters can explore science.
Participants at HHMI's undergraduate science education conference discuss techniques for determining the impact of their efforts.
Education conference at HHMI focuses on th eimpact of new technology on science education in the schools and other settings.
Garnett L. Keith, chairman of SeaBridge Investment Advisors L.L.C., in Summit, New Jersey, has been elected Trustee of the Howard Hughes Medical Institute, the nation's largest philanthropy.
Graeme Bell and other researchers have found a gene that may make people susceptible to type II diabetes.
Two HHMI physician postdoctoral fellows have developed Medsite Navigator to assist patients, physicians and researchers in locating high-quality medical and scientific information.
Scattered across reservations on the wind-swept plains of North Dakota, a network of schools is encouraging Native American students to pursue science.
The Institute brings together its international research scholars from 10 European countries, in the Czech capital.
A team of HHMI scientists has peered deep inside HIV-1 for a closer view of the fragile shell that envelops the virus' genetic material.
HHMI's international program brings together scientists from the Baltics, Central Europe and the former Soviet Union.
Dan Littman and fellow researchers have found a receptor for HIV that appears to play a key role in the transmission of the virus between individuals.
Michael Naski has helped to identify a genetic mutation that can cause bones to stop growing, leading to a form of dwarfism.
HHMI researchers have learned that basal cell carcinoma is caused by a defect in a gene that restrains cell growth.
HHMI scientists at the University of Texas Southwestern Medical Center are blocking the enzyme telomerase in a new strategy to prevent cancer cells from dividing.
Don Ganem's decision to search for a viral cause for Kaposi's sarcoma was considered risky by many molecular biologists.
Sharon Long's studies of signal transduction pathways in plants could yield insights into cancer and other diseases in humans.
Hughes researchers have developed a technique that may speed the identification of more tumor suppressor genes.
Changes in the health care system are leading some young physicians to reexamine their plans for combining research and clinical practice.
International research scholar Alec Jeffeys believes that radiation leaked from Chernobyl more than a decade ago may only now be manifesting its diastrous legacy.
Students at Texas Tech University are co-authors on a Nature paper showing a high rate of genetic change in rodents living near the Chernobyl reactor.
HHMI investigator Michael J. Welsh's research team has found that the airways of CF patients lack a natural substance that kills bacteria.
Hughes investigator Ronald D. Vale's research provides fresh insight into the structure and operation of the motor proteins that convert chemical energy in the cell into physical movement.
Experiments by Marc Caron and colleagues reveal the importance of the dopamine transporter in conditions such as addiction, schizophrenia and Parkinson's disease.
The discovery of a common genetic circuit for limb formation in arthropods is not only important for developmental biology, but also holds promise as an important new window to the past.
The Institute's Trustees accepted Helen K. Copley's resignation at their November meeting. Copley was one of the original group of Trustees appointed by the Delaware Court of Chancery in 1984.
Genes and partial gene sequences are being found at a rate far faster than anyone can decipher their function. Two groups of Hughes researchers have been attacking that bottleneck with automated programs designed to shed light on the function of newly found genes and the expression patterns of known genes.
Peter S. Kim, an HHMI investigator at the Whitehead Institute for Biomedical Research, believes that the coiled-coil structure of a protein may provide HIV with the spike it needs to infect cells.
James A. Baker, III, secretary of state under George Bush and secretary of the treasury under Ronald Reagan, has been elected a Trustee of HHMI.
HHMI investigator Kevin P. Campbell, HHMI associate Franck Duclos and University of Iowa College of Medicine M.D./Ph.D. student Leland Lim have identified a new form of muscular dystrophy and developed a screening test to detect carriers of the disease.
Daniel E. Goldberg and colleagues have discovered how the malaria parasite is able to safely sidestep a poison in hemoglobin, its main food source.
HHMI Investigator Ronald M. Evans has found a new hormone that triggers cells to become fat cells.
A team of U.S. and Finnish scientists led by HHMI investigator, David Page, has found that a specific defect in the Y chromosome may be responsible for 13 percent of cases of azoospermia, the inability to make sperm and the most severe form of male infertility.
A research group headed by HHMI investigator Richard D. Palmiter at the University of Washington has shown conclusively that catecholamines are essential in mouse development, and most likely in human development, too.
Leptin administered to overweight mice during two weeks of treatment caused the mice to decrease food intake and increase energy expenditure.
A team of U.S. and Finnish scientists has found that a specific defect in the Y chromosome may be responsible for 13 percent of cases of azoospermia, the inability to make sperm and the most severe form of male infertility.
Christine and Jonathan Seidman have developed a mouse model of familial hypertrophic cardiomyopathy that should greatly enhance genetic studies of this deadly disease.
The following remarks were made by Hungarian researcher László Hunyady of Semmelweiss University of Medicine in Budapest. He was addressing diplomats and journalists at a luncheon announcing the Hughes grants that was held in July at HHMI's headquarters outside of Washington, D.C.
HHMI researchers at Rockefeller University have discovered a new hormone produced by fat tissue and presumably acting on the brain to regulate weight.
Scientists at the Howard Hughes Medical Institute at Columbia University are turning their attention to proteins that might beckon to the correct DNA target within human cells.
Researchers with the Howard Hughes Medical Institute at Yale University led a team that found the genetic cause at the heart of Liddle's syndrome.
Researchers at the Howard Hughes Medical Institute at the University of Utah have discovered two genes that cause long QT syndrome, an inherited disorder that causes sudden death in young, otherwise healthy people.
Yuet Wai Kan's team at the Howard Hughes Medical Institute at the University of California, San Francisco, has devised a method for delivering a genetic message to tissues and cells displaying the same molecular "address."