New research has found that many of the symptoms of fragile X syndrome can be eliminated in mice by reducing the expression of a single gene.
Researchers have a new picture of how neurons forge physical connections between one another in order to communicate.
Even short bursts of activity in a few neurons can influence learning and decision making.
New findings help explain how the brain communicates with the inner ear, reducing its response to sound in loud or distracting environments.
Nuevo descubrimiento ayuda a explicar cómo se comunica el cerebro con el oído interno, reduciendo la respuesta al sonido en ambientes ruidosos o que distraen.
Despite a vast evolutionary gulf, humans and the three-spined stickleback fish have adopted a common genetic strategy to acquire the skin pigmentation that helps them thrive.
A team of researchers has exposed how one of the genes most commonly mutated in human cancers helps good cells go bad.
A pesar de la gran brecha evolutiva que existe entre los seres humanos y el pez espinoso de tres espinas, las dos especies han adoptado una estrategia genética común para adquirir la pigmentación de la piel que ayudaría a estas dos especies a prosperar en su nuevo ambiente.
Equipo de investigadores expone la forma en la que uno de los genes que más comúnmente muta en los cánceres humanos puede hacer que las células buenas se conviertan en malignas.
Twelve colleges and universities have been selected to participate in a nationwide genomics course that will involve first-year college students in authentic research.
New research shows that normal aging appears to disrupt communication between different regions of the brain.
Nueva investigación muestra que el envejecimiento normal parece interrumpir la comunicación entre distintas regiones del cerebro.
Dr. Vijay K. Samalam joins Janelia Farm from the San Diego Supercomputer Center.
The antidepressant mianserin can extend the lifespan of the the roundworm by about 30 percent.
Structural information about the protein the measles virus uses to attach itself to target cells suggests a strategy to fight infection.
HHMI investigator Dorothee Kern and her colleagues have developed a new picture of how the enzyme adenylate cyclase works.
Información estructural sobre la proteína que usa el virus del sarampión para unirse a sus células dianas podría proporcionar una nueva estrategia para luchar contra la infección.
Janelia Farm is seeking up to 8 college students to pursue research projects with Janelia Farm scientists during Summer 2008.
Researchers have deciphered the molecular language that cholera bacteria use to coordinate their infectivity. By interrupting the bacterium's chemical conversation, researchers may be able to stop cholera virulence.
HHMI researchers are unveiling the most detailed views yet of the structure of a voltage-dependent potassium ion channel.
Unos investigadores han descifrado el lenguaje molecular que las bacterias del cólera utilizan para coordinar su infectividad. Al interrumpir la conversación química de las bacterias, se podría detener la virulencia del cólera.
Researchers have developed a small molecule that can turn the survival signal for a variety of cancer cells into a death signal.
New details emerge about how cells decide their fates when faced with stress.
Researchers have devised a new strategy to fight breast and ovarian cancer.
Scientists have shown how odor-sensing neurons in the worm can activate or inhibit other neurons that control crawling and turning.
New studies reveal that the cancer-promoting gene ras relies on 28 other genes to switch off the cell's programmed cell death pathway.
HHMI researchers discover a clever strategy that helps Legionella pneumophila infect host cells.
HHMI researchers have now discovered a protein that can affect how DNA is packaged inside sperm.
A worldwide network of more than 150,000 home computer users helped HHMI researchers predict the structure of a small, naturally occurring protein.
The brain may continue to consider the options even after a decision is made, leaving room for a change of mind.
Six HHMI investigators and an international research scholar have been elected to the Institute of Medicine of the National Academies.
New study suggests that each breast and colon tumor is unique and may arise through mutations in many different combinations of genes.
HHMI announces the selection of 15 of the nation's top patient-oriented researchers, who will soon become HHMI investigators.
Meet the 15 physician-scientists selected in 2007 as new HHMI investigators.
HHMI investigator Mario R. Capecchi is among trio of scientists honored for development of powerful gene-targeting techniques.
Mario Capecchi received a Kyoto Prize from the Inamori Foundation in 1996. The lecture he delivered when he accepted the prize in Japan in November 1996 tells the story of his remarkable life. The text of the lecture has been edited for length.
New studies establish how the stress hormone norepinephrine boosts learning by strengthening connections between neurons.
Scientists have traced the 170 million-year evolution of a piece of "junk" DNA to its modern incarnation as an important regulator of energy balance.
Científicos rastrean la evolución que tuvo, durante 170 millones de años, un pedazo de ADN “basura” hasta encontrar su encarnación moderna como regulador importante del balance energético.
HHMI researchers have figured out how a bacterial circadian clock ticks away using only three interacting proteins.
The Science Education Alliance, headquartered at Janelia Farm, will become a national network of scientists and educators working collaboratively to develop and distribute new materials and methods to the education community.
Under Springer's Open Choice program, articles are immediately published with full open access and deposited in repositories such as PubMed at a flat-rate fee per article.
Researchers have demonstrated how tens of thousands of closely related proteins establish the specificity that allows them to serve as identification tags for individual neurons.
Researchers have determined the identity of a significant feature that makes a neuron a recycler par excellence.
Scientists have succeeded in reprogramming adult stem cells from the testes of male mice into functional blood vessels and contractile cardiac tissue.
A chemical produced when the body breaks down cholesterol inhibits the activity of estrogens circulating in the blood.
Individual variability in innate immunity may leave some people dangerously exposed to common pathogens such as herpes simplex virus.
A genetic mutation found in some people with autism and Asperger syndrome causes social impairment and cognitive enhancement in mice.
Researchers have provided insight into how mutations in a single gene can cause mental retardation and kidney dysfunction in boys with Lowe syndrome.
Studies reveal why the same prion protein can be either weakly or strongly infectious.