A new analysis suggests that the regulatory protein MeCP2 works with the modified nucleotide 5hmC to facilitate gene activation in the brain.
Scientists have discovered the molecular pathway responsible for detecting loose bits of DNA outside a cell’s nucleus and setting off an immune reaction.
Rather than scrutinizing hours of video, scientists can quickly teach the software how to recognize key behaviors.
AAAS recognizes Ulrike Heberlein and Nelson Spruston for meritorious efforts to advance science.
O'Shea, HHMI investigator and professor at Harvard University, will lead HHMI's science programs.
New film and media production company aims to be a significant contributor to the science documentary arena.
Betzig will discuss historical connections between astronomy and microscopy on Dec. 12.
A new DNA sequencing technique has enabled researchers to map for the first time the influential chemical modifications known as methylation marks throughout the genome of a pathogenic bacterium.
Susan Desmond-Hellmann, M.D., M.P.H., chancellor of the University of California, San Francisco, becomes one of 11 Trustees of the Institute.
Hanna H. Gray, Ph.D., former chair of the HHMI Trustees, retires after serving the Institute since 1984.
Sean Carroll introduces "The Day the Mesozoic Died" at national teachers conference.
Seven HHMI investigators and two members of HHMI’s Scientific Review Board have been elected to the Institute of Medicine of the National Academies.
eLife makes first collection of research articles available online.
Robert Lefkowitz de HHMI comparte el premio con Brian Kobilka por estudios sobre los receptores acoplados a proteínas G.
Only a few animals, such as songbirds, whales, and dolphins, are known to be vocal learners, modifying the sequence or pitch of their sounds based on what they hear from other members of their species. New evidence suggests mice can be added to that list.
HHMI's Robert Lefkowitz shares prize with Brian Kobilka for research on G-protein coupled receptors.
HHMI and the University of KwaZulu-Natal open new research institute in Durban, South Africa.
In experiments with rats, researchers found that the rejection of an old belief correlates with abrupt changes in activity in a region of the brain involved in cognitive functions such as reward anticipation and decision-making.
HHMI selects 13 of the world’s leading basic science researchers to receive Senior International Research Scholar (SIRS) awards. The awards support outstanding biomedical scientists working outside the United States who have made significant contributions to fundamental research in the biological sciences.
HHMI awards three two-year grants to aid in developing the next generation of interdisciplinary scientists, in collaboration with the National Institute of Biomedical Imaging and Bioengineering.
HHMI investigator Ronald D. Vale of UCSF will share the 2012 Albert Lasker Basic Medical Research Award.
Together, the teams include 28 researchers from 20 institutions in the United States, Germany, and Israel.
Thousands of genes in organs throughout the body show predictable daily fluctuations. New research reveals complexity in how those genes' cycles of activity are controlled.
A discovery of how ethylene triggers changes in gene activity could lead to new ways to stop or slow ripening.
Nine students, listed below with their undergraduate institutions, were selected as Gilliam fellows in 2012.
The first-ever three-dimensional image of an isolated kinetochore suggests how it maintains its grip on microtubules as they pull chromosomes to the ends of a dividing cell.
The vaccinia virus increases the size of its genome when it confronts the immune system, thereby increasing the odds of a random mutation that will improve its survival.
By investigating the cause of a fatal snake disease, scientists have found a virus that links two known virus families that can cause fatal hemorrhagic fevers in humans.
Mutations in four different DNA damage repair genes have been linked to chronic kidney disease.
Scientists have catalogued and compared the hundreds of types of bacteria that associate with the roots of the model plant Arabidopsis under various conditions.
HHMI has awarded more than $2 million in fellowships to 50 promising graduate students from 19 countries.
Meet the 2012 International Student Research Fellows
Nurse's lecture on "Great Ideas of Biology" will take place at HHMI's Janelia Farm Research Campus on July 31.
With a newly discovered component of an adaptive bacterial immune system, scientists have identified a targeted method of slicing DNA that they say can be easily customized for a variety of applications.
Short strands of piwi-interacting RNA may detect foreign invaders by determining whether a gene has ever been turned on in an organism's past.
Quake is being recognized for his work in drug discovery, genome analysis and personalized medicine.
A new imaging technology developed at Janelia lets users track each cell in an embryo as it takes shape over hours or days.
Thirty years after their discovery, scientists have the first picture of a Wnt protein, a member of a protein family that includes some of the most important regulators of growth and development.
HHMI scientists have determined the three-dimensional structure of two proteins that help keep the body's clocks in sync.
The three scientists are recognized for elucidating basic neuronal mechanisms underlying perception and decision.
Arthur Horwich and Franz-Ulrich Hartl honored for contributions to the understanding of the molecular mechanism of protein folding.
Using genetic programming, researchers have identified a specific type of cell in the outer layers of the brain that is crucial for Prozac's action.
A list of the 47 small colleges and universities awarded a four-year grant in HHMI's science education initiative.
Colleges receive funds to incubate new science education courses and programs.
Seventy students from 27 medical schools across the country will participate in HHMI's year-long Medical Research Fellows Program.
Researchers lay out evidence for how an unusually efficient enzyme evolved from non-catalytic ancestor proteins.
In the region of the brain that controls motor planning, a self-reinforcing loop of neuronal signaling helps establish connectivity during early development.
Researchers have uncovered the enzyme that transfers phosphate to milk proteins like casein, but also to proteins found in bones and teeth enamel.
Dixon, who has led HHMI's scientific programs since 2007, will retire from the Institute in summer 2013.
Fourteen HHMI scientists are among 84 newly elected members.