Scientists show they can control whether mice perceive a taste as bitter or sweet by activating two small areas of the brain.
HHMI investigators Karl Deisseroth and Helen Hobbs are among five scientists honored for transformative advances toward understanding living systems and extending human life.
HHMI scientists have identified a set of proteins that plays a surprisingly broad role in guiding tissue formation in plant roots.
Within less than a second, the new IsoView microscope produces images of entire organisms, such as a zebrafish or fruit fly embryo, with enough resolution in all three dimensions that each cell appears as a distinct structure.
HHMI's Paul Modrich shares 2015 Nobel Prize in Chemistry with Tomas Lindahl and Aziz Sancar for studies of DNA repair.
New research indicates individual human neurons may harbor up to 1,000 genetic mutations.
HHMI Investigator Stephen Elledge of Brigham and Women's Hospital shares the 2015 Albert Lasker Basic Medical Research Award with Evelyn Witkin of Rutgers University.
HHMI and the Zooniverse launch WildCam Gorongosa, a new citizen science project.
New imaging methods dramatically improve the spatial resolution provided by structured illumination microscopy, one of the best imaging techniques for seeing inside living cells.
HHMI scientists have discovered how the most common genetic defect in amyotrophic lateral sclerosis kills nerve cells.
Four HHMI scientists are among those honored by the prestigious Royal Society.
HHMI researchers solve a longstanding mystery about the origin of new cells in the liver.
HHMI President Robert Tjian will step down in late 2016.
On September 16, Matthew Scott, President of the Carnegie Institution for Science, will deliver a talk, “Exploring the Genes that Built You” at Janelia Research Campus.
HHMI selects 45 predoctoral students from 18 countries to receive fellowships that will help them complete their graduate degrees in the life sciences.
A lipid molecule called EET helps blood-forming stem cells replenish the immune system.
New research begins to explain how plants separate microbes they like from those they don't like.
The Howard Hughes Medical Institute’s newly expanded Gilliam Fellowships for Advanced Study Program has awarded 30 fellowships to outstanding students who are pursuing a PhD in the life sciences and who are committed to increasing diversity among scientists.
HHMI scientists have profiled key features of the genetic material inside three types of brain cells and found vast differences in the patterns of chemical modifications that affect how the genes in each type of neuron are regulated.
New studies provide the first genetic evidence that humans interbred with Neanderthals in Europe.
HHMI announces five-year, $2.3 million grant to support educational activities and infrastructure development at the E.O. Wilson Biodiversity Laboratory in Gorongosa National Park, Mozambique.
New technology developed by HHMI researchers makes it possible to test for current and past infections with any known human virus by analyzing a single drop of blood.
Bassler shares prestigious honor for discovery of quorum sensing, a process that allows bacteria to communicate with each other.
Meet the new 2015 HHMI Investigators.
Meet the new 2015 HHMI Investigators.
An accomplished group, the 26 new HHMI investigators are at the forefront of discovery research.
New research hints at strategies fruit flies use to keep track of where they are going, even when it's dark.
HHMI's new science education initiative is challenging colleges and universities to increase their capacity to engage all students in science.
Studying fruit fly larvae, Janelia scientists have mapped the entire neural circuit involved in combining vibration and pain sensations used in triggering an escape behavior.
HHMI scientists are among 84 newly elected members.
Thousands of undergraduate students contribute to new study that broadens understanding of genetic diversity of bacteriophages.
Negative emotions associated with hunger can make it hard to maintain a diet and lose weight. Hunger-sensitive cells in the brain may help explain that struggle.
Eleven HHMI scientists are elected to the American Academy of Arts and Sciences.
Sixty-eight medical and veterinary students from 37 different schools across the country will participate in HHMI's year-long Medical Research Fellows Program.
HHMI researchers develop a new single-cell imaging technique that reveals the copy numbers and locations of thousands of RNA molecules inside a cell.
On May 13, Princeton University President Emerita Shirley Tilghman will deliver a talk, “The Wild and Wacky World of Epigenetics” at 7:00 p.m. at Janelia Research Campus.
HHMI researchers identify a rare genetic mutation that tamps down immune response to influenza.
HHMI, the Bill & Melinda Gates Foundation, and the Simons Foundation launch Faculty Scholars Program to give promising early-career scientists a boost.
HHMI scientists have designed a revolutionary "3D printer" for small molecules that could open the power of customized chemistry to many.
Scientist at Janelia Research Campus wins The Brain Prize for helping to develop a tool that advances our understanding of how the brain's networks process information.
A new way of thinking challenges standard notions about what a herpes vaccine should look like.
Scientists at Janelia Research Campus have identified a neural circuit that connects motor planning to movement.
A new tool developed at HHMI's Janelia Research Campus lets scientists permanently mark neurons that are active at a particular time.
New studies by HHMI scientists show how cells use sophisticated signaling mechanisms to control production of interferon.
HHMI researchers have identified a neural circuit in the subfornical organ that regulates thirst in mice.
When battling a chronic infection, killer T cells must take a break so they can continue to fight off infection.
Janelia researchers show that Hox proteins trigger gene activity through weak interactions at previously unrecognized DNA binding sites in the genome.
On February 18, Janelia group leader Luke Lavis will speak about “The Chemistry of Color” at 7:00 p.m. at Janelia Research Campus.
Scientists have determined new structures of an essential cellular recycling machine with near atomic-level detail. The structures, which show a protein called NSF alone and interacting with its target, a protein complex called SNARE that is formed when membranes fuse together.
HHMI scientists and their colleagues discover a new mechanism of protein synthesis.