HHMI researchers have identified 27 genes in brain stem cells that are prone to a type of DNA damage called double-strand breaks.
Scientists have identified a genetic regulator that controls the reshuffling of gene segments in immune cells.
In mending the DNA broken during antibody production, immune cells can employ a type of DNA repair that is fundamentally different than the classical method.
Researchers have learned how the immune system slices and dices genes so B cells can program antibodies to seek out and destroy invaders.
Researchers have created a mouse model that closely mimics the most common childhood brain tumor.
Knocking out a gene that helps repair nicks in DNA causes young mice to develop many of the degenerative characteristics of their wizened elders.
HHMI researchers have determined that a gene present in mouse cells limits the number of times that a cell can divide.
HHMI researchers discover new component of the machinery immune cells use to generate diverse array of antibodies.
HHMI researchers have discovered a new culprit that can induce instability in the genome and thereby set the stage for cancer to develop.
HHMI researchers discover new details about how the immune system generates antibodies.
HHMI researchers identify a protein that protects against DNA damage.