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Scientists have identified a genetic regulator that controls the reshuffling of gene segments in immune cells.
In mending the DNA broken during antibody production, immune cells can employ a type of DNA repair that is fundamentally different than the classical method.
Researchers have learned how the immune system slices and dices genes so B cells can program antibodies to seek out and destroy invaders.
Researchers have created a mouse model that closely mimics the most common childhood brain tumor.
Knocking out a gene that helps repair nicks in DNA causes young mice to develop many of the degenerative characteristics of their wizened elders.
HHMI researchers discover new component of the machinery immune cells use to generate diverse array of antibodies.
HHMI researchers have discovered a new culprit that can induce instability in the genome and thereby set the stage for cancer to develop.
Investigadores del HHMI han descubierto a nuevo culpable que puede inducir inestabilidad genómica y por ello puede allanar el camino para el desarrollo de cáncer.
HHMI researchers discover new details about how the immune system generates antibodies.
Investigadores del HHMI descubren nuevos detalles sobre la forma en la que el sistema inmune genera anticuerpos.
Las roturas cromosómicas y los reordenamientos genéticos suceden cuando se inactiva un sistema específico de reparación de ADN.
Investigadores del HHMI identifican a una proteína que protege del daño en el ADN.
HHMI researchers identify a protein that protects against DNA damage.
