New HHMI research shows that reactivating fetal hemoglobin production in adult mice effectively reverses sickle cell disease.
By manipulating a newly identified regulatory protein, researchers can reactivate a dormant fetal hemoglobin gene--possibly with therapeutic benefits for patients with life-threatening anemias.
HHMI researchers have developed a mouse model of osteosarcoma, the most common form of bone cancer.
Researchers have identified hundreds of genes that keep embryonic stem cells in their characteristic malleable state.
Researchers have created a map of the protein landscape that regulates a stem cell's ability to differentiate into multiple types of mature cells.
A new mouse model may help researchers understand a rapidly advancing cancer that affects children.
Un nuevo modelo en ratón ayuda a que los investigadores comprendan un cáncer de avance rápido que afecta a niños.