Scientists have determined new structures of an essential cellular recycling machine with near atomic-level detail. The structures, which show a protein called NSF alone and interacting with its target, a protein complex called SNARE that is formed when membranes fuse together.
Together, the teams include 28 researchers from 20 institutions in the United States, Germany, and Israel.
Researchers have a new picture of how neurons forge physical connections between one another in order to communicate.
Two HHMI research teams have discovered new information about how the botulinum neurotoxin shuts down neurons with deadly efficiency.
New studies show how the toxins that cause botulism and tetanus can recognize and attack particular nerve cell proteins at the neuromuscular junction.
HHMI researchers produce the first glimpses of the molecular machinery that propels neurotransmitters into the synapse.