A new drug target could defeat HIV's rapid evolution, its main mechanism of drug resistance.
HHMI researchers have determined the three-dimensional structure of a protein-RNA complex that shepherds the production of infectious copies of HIV. The structure is a promising target for new antiviral drugs. Article published in the January 16, 1998 issue of Science.
A team of HHMI scientists has peered deep inside HIV-1 for a closer view of the fragile shell that envelops the virus' genetic material.