New evidence suggests that aneuploidy patterns of chromosome deletion or amplification that are recurrent among tumors actually represent a driving force during tumor evolution and are very frequent in cancer.
Stephen Elledge recognized for research on DNA repair.
Triple-negative tumors lack three traits that can be targeted by available breast cancer treatments. But new findings suggest treatment possibilities for these aggressive cancers may be at hand.
Researchers have identified a naturally occurring human protein that helps prevent infection by H1N1 influenza and other viruses, including West Nile and dengue virus.
HHMI researchers identify many potential new drug targets for cancers long deemed "untouchable."
HHMI investigators are beginning to examine every gene in the genome to figure out which genes are deleterious to tumor cells.
Researchers have identified 273 host proteins that serve to keep the AIDS virus healthy and happy as it infects cells.
A new database created by HHMI researchers reveals a 700-member strong army of proteins involved in the DNA repair response.
RNA libraries should greatly speed gene analysis and discovery.
The protein produced by the BRCA2 gene participates in DNA repair.
Researchers find a protein that activates the tumor suppressor p53.
HHMI researchers at Baylor College of Medicine have identified a protein that works closely with BRCA1 to initiate the repair of damaged DNA. They say that mutations in the gene that produces this BRCA1 trigger protein may be responsible for more instances of breast cancer than BRCA1 mutation.