With the help of yeast and fruit flies, researchers have identified a distorted gene that appears to be among the most common genetic risk factors for amyotrophic laterial sclerosis (ALS), the devastating neurodegenerative disease also known as Lou Gehrig's disease.
A mutant RNA may be partially to blame for the neurodegeneration associated with spinocerebellar ataxia type 3.
Researchers have developed a fruitfly model that replicates the genetic instability seen in a variety of neurodegenerative diseases.
Defects in a critical cellular pathway can lead to symptoms of Parkinson's disease.
An enzyme that helps cells dispose of unwanted proteins may actually protect against a class of inherited brain disorders.
HHMI researchers show that a human protein can protect fruit fly neurons from neurodegeneration.