Howard Hughes Medical Institute (HHMI) scientists have created a portrait of a DNA-snipping protein called Cas9, a powerful research tool used in many labs for genome editing.
New research from HHMI scientists reveals how a foreign-DNA-destroying system, known as CRISPR, efficiently locates its DNA targets within a bacterial genome.
With a newly discovered component of an adaptive bacterial immune system, scientists have identified a targeted method of slicing DNA that they say can be easily customized for a variety of applications.
Researchers have new details of how an enzyme helps bacteria slice up foreign genetic material.
HHMI researchers have identified an "emergency" mechanism that yeast cells use to switch on protein synthesis in times of stress.
HHMI scientists peel back some of the mystery about how cells are able to turn off genes selectively.
Howard Hughes Medical Institute researchers have deduced the structure of a molecule that orchestrates the early stages of protein synthesis.
HHMI investigators report that the hammerhead ribozyme might have evolved multiple times.
HHMI researchers discover HCV's unusual mechanism for inducing synthesis of viral proteins.
HHMI researchers show that ribozymes and enzymes are ready to perform their biological function as soon as they are produced.