Using novel computational and biochemical approaches, HHMI scientists have designed and built from scratch 10 large protein icosahedra that are similar to viral capsids that carry viral DNA.
A cooperative online game has attracted 50,000 players whose “distributed thinking” has, in some cases, proven more powerful than computers in predicting the structure of proteins.
HHMI researchers bring the arcane world of protein folding to the online gaming arena with the launch of "Foldit."
Investigadores del HHMI acercan el arcano mundo del plegamiento proteico al terreno de juegos en Internet con el lanzamiento de “Pliégalo”.
Researchers have designed and built two functional enzymes never seen in nature.
A worldwide network of more than 150,000 home computer users helped HHMI researchers predict the structure of a small, naturally occurring protein.
Researchers have demonstrated how tens of thousands of closely related proteins establish the specificity that allows them to serve as identification tags for individual neurons.
Computers can predict the detailed structure of small proteins nearly as well as experimental methods, at least some of the time.
Computers can predict the detailed structure of small proteins nearly as well as experimental methods, at least some of the time, according to new studies by HHMI researchers. The findings provide a glimmer of hope that scientists eventually may be able to determine the structure of proteins from their genomic sequences, a problem that has seemed insurmountable.
Utilizando algoritmos computacionales sofisticados ejecutados en computadoras estándares, investigadores del HHMI han diseñado y construido una proteína funcional nueva que no se encuentra en la naturaleza.
HHMI researchers develop computer program that engineers a protein to fold 100-times faster than normal.
A computational method developed by HHMI investigators predicts the three-dimensional structure of proteins with surprising accuracy.