HHMI investigators Stephen Elledge, Roel Nusse and Huda Zoghbi are among the scientists honored for transformative advances toward understanding living systems and extending human life.
HHMI Investigator Stephen Elledge of Brigham and Women's Hospital shares the 2015 Albert Lasker Basic Medical Research Award with Evelyn Witkin of Rutgers University.
New technology developed by HHMI researchers makes it possible to test for current and past infections with any known human virus by analyzing a single drop of blood.
Nueva tecnología desarrollada por investigadores del HHMI hace que se pueda utilizar una gota de sangre de una persona para analizar infecciones presentes y pasadas con cualquier virus humano conocido.
New evidence suggests that aneuploidy patterns of chromosome deletion or amplification that are recurrent among tumors actually represent a driving force during tumor evolution and are very frequent in cancer.
Stephen Elledge recognized for research on DNA repair.
Triple-negative tumors lack three traits that can be targeted by available breast cancer treatments. But new findings suggest treatment possibilities for these aggressive cancers may be at hand.
Researchers have identified a naturally occurring human protein that helps prevent infection by H1N1 influenza and other viruses, including West Nile and dengue virus.
HHMI researchers identify many potential new drug targets for cancers long deemed "untouchable."
HHMI investigators are beginning to examine every gene in the genome to figure out which genes are deleterious to tumor cells.
Researchers have identified 273 host proteins that serve to keep the AIDS virus healthy and happy as it infects cells.
A new database created by HHMI researchers reveals a 700-member strong army of proteins involved in the DNA repair response.
RNA libraries should greatly speed gene analysis and discovery.
Investigadores han producido extensas bibliotecas de ARN que pueden ser utilizadas para inactivar genes individuales de ratón y de seres humanos para estudiar su función.
The protein produced by the BRCA2 gene participates in DNA repair.
La proteína producida por el gen BRCA2 participa en la reparación del ADN.
Researchers find a protein that activates the tumor suppressor p53.
Investigadores encuentran una proteína que activa al supresor tumoral p53.
HHMI researchers at Baylor College of Medicine have identified a protein that works closely with BRCA1 to initiate the repair of damaged DNA. They say that mutations in the gene that produces this BRCA1 trigger protein may be responsible for more instances of breast cancer than BRCA1 mutation.
Investigadores del Instituto Médico Howard Hughes (HHMI), en el Colegio de Medicina Baylor, han identificado una proteína que trabaja junto con BRCA1 para iniciar la reparación del ADN dañado. Ellos dicen que mutaciones en el gen que produce esta proteína activadora de BRCA1 pueden ser las responsables de más casos de cáncer que los producidos por mutaciones en BRCA1.