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New research reveals details of changing DNA methylation patterns as the brain matures.
Proteins engineered to bind enhancer regions of the genome offer researchers a window into how genes are activated.
Scientists have identified a gene that enables wheat crops to fight off stem rust, a dreaded fungus that blights wheat fields with rusty brown lesions and reduces yields.
When injected into mice immediately following a traumatic event, a new drug prevents the animals from developing memory problems and increased anxiety that are indicative of post-traumatic stress disorder.
In one of the first successful attempts at genetically engineering mosquitoes, researchers have altered the way the insects respond to odors, including the smell of humans and the insect repellant DEET.
Malaria parasites infecting human red blood cells send packets of information between cells to coordinate group activity. When the parasites are under stress, the communication increases their ability to develop into a new stage of the life cycle.
New research shows that about 10 percent of severe cases of congenital heart disease are caused by genetic mutations that are absent in the parents of affected children.
Waging an immunological war against a pathogen is not the body’s only way to survive an infection. Sometimes learning to live with an invader can be just as important.
Scientists have discovered a hormone that causes the body’s insulin-producing factories, beta cells, to churn out more of themselves.
A new technique transforms biological tissue into an optically transparent sample that retains its original structure and molecular information.
Stephen Elledge recognized for research on DNA repair.
New research reveals how a localized source of a signaling molecule directs a dividing stem cell to produce two different cells—one identical to its parent, the other a more specialized cell type—and aligns those cells.
Researchers have found that temperatures on the surface of the tropical South Atlantic Ocean in July can predict the severity of malaria outbreaks in northwestern India that begin to peak four months later.
Scientists have a new view of the cellular machinery that assembles directly on DNA and readies it for transcription into RNA, the first step in protein production.
Three HHMI scientists are among 11 honored for excellence in research aimed at curing intractable diseases and extending human life.
Scientists have discovered that periodic ring-shaped actin arrangements encircle the long axonal fibers of nerve cells, in contrast to the linear meshworks that typically give cells their shapes.
HHMI scientists discover how a single molecule in a living cell can respond differently to different strengths of an external signal.
A new analysis suggests that the regulatory protein MeCP2 works with the modified nucleotide 5hmC to facilitate gene activation in the brain.
Scientists have discovered the molecular pathway responsible for detecting loose bits of DNA outside a cell’s nucleus and setting off an immune reaction.
Rather than scrutinizing hours of video, scientists can quickly teach the software how to recognize key behaviors.
AAAS recognizes Ulrike Heberlein and Nelson Spruston for meritorious efforts to advance science.
