Force-Gated Ion Channels: From Structure to Sensation
May 18 - 21, 2008

Recent structural data has shed new light on the mechanism of action of mechanically gated channels in prokaryotes. Genetics of simple animals like worms and flies has revealed good candidates for mechanically gated channels that mediate touch sensation in eukaryotes. Still unclear are what channels underlie senses like hearing and touch in mammals, and how any of the eukaryotic channels gate in response to mechanical force. This meeting brought together structural and sensory biologists working at all different levels of mechanosensation, to focus on the mechanisms of mechanical sensing by ion channels.

• ORGANIZERS:

  David Corey, HHMI/ Harvard
  
  Ellen Lumpkin, Baylor College of Medicine

• INVITED PARTICIPANTS:

  Cornelia Bargmann HHMI/ Rockefeller University Charles Bourque McGill University Peter Gillespie Oregon Health & Science University/ The Vollum Institute Miriam Goodman Stanford University School of Medicine Martin Gopfert Universitat zu Koln Owen Hamill University of Texas Medical Branch Eric Honore Institut de Pharmacologie Moleculaire et Cellulaire Jonathon Howard Max Planck Institute, Dresden A. James Hudspeth HHMI/ Rockefeller University Changsoo Kim Chonnam National University Ching Kung University of Wisconsin Pascal Martin Institut Curie/CNRS

  Christopher Moore Massachusetts Institute of Technology Ulrich Mueller The Scripps Research Institute Teresa Nicolson HHMI/ The Vollum Institute Bernd Nilius Katholieke Universiteit Leuven Anthony Ricci Stanford University School of Medicine Marcos Sotomayor University of Illinois at Urbana-Champaign Sergei Sukharev University of Maryland Dan Tracey Duke University John Wood University College London Shawn Xu University of Michigan Charles Zuker HHMI/ University of California San Diego

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