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Our goal is to enrich the science experiences of the teachers and students of California through a comprehensive program of technology, hands-on, and research-based experiences. The components of this integrated biomedical outreach partnership include: 1) The technology-situated problem solving IMMEX Project (UCLA); 2) The state of the art molecular biology hands-on classroom activities of outreach partners in San Francisco (MMRI, BABEC); and 3) A combined faculty, teacher, high school student research partnership program. The first two components are well-established programs having individually impacted hundreds of teachers and thousands of students and, when combined through this program's activities will provide new insights into the effective interactions among these different instructional modalities. The third component is an experimental extension of these established programs that will create 24 faculty/teacher/student research partnerships, expanding the opportunities for our 300+ teachers who have already participated in month-long IMMEX outreach activities. These partnerships will enrich the experiences of students aspiring for a research career, and expand the science content/process knowledge of the teachers. The requested funding from HHMI will provide the "glue" to integrate these components into what we envision as a very unique and effective science partnership that will impact teachers and students (over 70% minority) directly in two major metropolitan areas and indirectly across the country via the IMMEX technology. The proposal has a strong assessment component, including tracking, and through commitments from the UCLA School of Medicine, the Los Angeles Unified School District, and individual school principals, contains an extensive sharing component.
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