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1999 Research Resources Grant Awards
Albert Einstein College of Medicine
New York, New York
$1.6 million over four years is being used to (1) augment start-up packages for six junior faculty in the fields of genetic and translational medicine (e.g., bioinformatics, transgenic animal development, genomic/protein approaches to cancer, heart disease, autoimmune disorders, central nervous system disorders, infectious diseases, liver disease, diabetes, and MRI for analysis of transgenic models and human disease states); (2) provide equipment and operating support for an MRI laboratory and core facilities for molecular and human genetics, analytical imaging, and structural genomics and protein production; and (3) support the career development of junior faculty through travel awards for scientific meetings and the conduct of research symposia.
Baylor College of Medicine
Houston, Texas
$2.8 million over four years is being used to (1) provide start-up packages for four junior faculty, with research interests in complex trait analysis, database mining and analysis, and protein folding and interaction, to staff a new interdepartmental research center and (2) provide data storage and analysis software and some funds for salary in support of a DNA array core facility that provides low-cost mouse and human DNA chips for Baylor faculty.
Boston University School of Medicine
Boston, Massachusetts
$1.6 million over four years is being used to (1) provide start-up packages for two junior faculty (one with expertise in homologous recombination, the other with expertise in gene mapping and gene structure); (2) provide equipment and salary support to develop a gene knockout core facility and a gene mapping and gene structure core; and (3) renovate an animal care facility to be used for the gene knockout core.
Case Western Reserve University School of Medicine
Cleveland, Ohio
$3 million over four years is being used to (1) support start-up packages for eight junior faculty in the fields of structural biology, neuroscience, and genetics/genomics and (2) purchase an X-ray crystallographic image plate detector to be used by the departments of biochemistry, molecular biology, neurosciences, and genetics.
Columbia University College of Physicians and Surgeons
New York, New York
$2.4 million over four years is being used to support start-up packages for four assistant professors who will establish a program in systems biology to study organogenesis, systems neurobiology, cardiovascular pathogenesis, and immune regulation.
Dartmouth Medical School
Hanover, New Hampshire
$3.4 million over four years is being used to provide (1) start-up packages for seven junior faculty to support a newly established genetics department; (2) equipment and salary support for macromolecular analysis and transgenic core facilities; (3) equipment needed to establish a new structural biology X-ray crystallography laboratory; and (4) support for minor laboratory renovations to support the work of investigators hired through this grant.
Duke University School of Medicine
Durham, North Carolina
$2.4 million over four years is being used to provide (1) start-up packages for four junior faculty (two in the basic sciences and two in the clinical sciences) at the newly established Institute for Genome Sciences and Policy for working in areas such as human and murine genomics, integrative biology, structural biology, and bioinformatics; (2) equipment and salary support to enhance an NMR core facility and establishment of laboratories in a new phenotyping core facility to assess murine behavior and mouse cardiovascular function; and (3) support for five pilot projects at the interface of clinical and basic research.
Emory University School of Medicine
Atlanta, Georgia
$1.6 million over four years is being used to (1) support the development of a small animal neuroscience imaging core facility, a flow cytometry and cell sorting core, and a biochip microarray core and (2) support laboratory renovation required for installation of MicroPET instrumentation.
Harvard Medical School
Boston, Massachusetts
$1.8 million over four years is being used to (1) support start-up packages for two assistant professors in the areas of bioinformatics and computational biology; (2) provide equipment and salary support to establish a Center for the Study of Disease Models; (3) expand the Research Computing Center through salary support for a research scientist who will provide informatics training; and (4) provide funding for seed grants to develop collaborative, interdisciplinary projects with preference for translational research.
Mayo Medical School
Rochester, Minnesota
$1.6 million over four years is being used to (1) provide salary support for the new molecular epidemiology function of the Cancer Center's gene discovery core facility; (2) provide operating support for a gene therapy vector production facility in the molecular medicine program; and (3) support the newly established Center for Patient-Oriented Research.
Mount Sinai School of Medicine
New York, New York
$2 million over four years is being used to (1) support start-up packages for four junior faculty (two with research interests in cardiovascular development and degeneration, two with expertise in bioinformatics and imaging sciences); (2) provide a multiphoton system for a microscopy core facility and salary support for a magnetic resonance microscopy core; and (3) support pilot research projects, developed in collaboration with the Institute for Advanced Study and the Courant Institute for Mathematical Sciences, to explore the interface of biology, mathematics, and computation.
Northwestern University School of Medicine
Chicago, Illinois
$2 million over four years is being used to (1) provide start-up packages for eight junior faculty (six in genetics and two in neuroscience) and (2) defray user expenses for a transgenic core facility and purchase an Affymetrix workstation and other equipment for a macromolecular analysis core.
Oregon Health Sciences University School of Medicine
Portland, Oregon
$1.8 million over four years is being used to support start-up packages for seven junior faculty whose research focuses on the molecular or developmental basis of disease: four packages will be allocated for basic science departments and three for physician-scientists working in the molecular medicine unit in the department of medicine.
Stanford University School of Medicine
Stanford, California
$1.6 million over four years is being used to support three core facilities: a transgenic mice core that will perform embryonic stem cell transfections with gene targeting vectors, a DNA microarray core that will enable investigators to create custom arrays based on either genomic sequence or cDNAs, and a core for producing monoclonal antibodies.
State University of New York at Buffalo, School of Medicine and Biomedical Sciences
Buffalo, New York
$3.8 million over four years is being used to (1) support start-up packages for five junior faculty (in computational chemistry, structural biology, and molecular dynamics) to be hired for the Center for Single-Molecule Biophysics and (2) provide equipment and salary support for the Center for Single Molecule Biophysics and the Center for Genomics and Proteomics.
State University of New York at Stony Brook, Health Sciences Center School of Medicine
Stony Brook, New York
$2 million over four years is being used to support research in the new Centers for Molecular Medicine, specifically (1) start-up packages for seven junior faculty in the areas of cancer, cancer genetics, structural biology, and infectious disease; (2) equipment for transgenic mouse, NMR, X-ray crystallography, and computational core facilities; (3) purchase of an automated DNA sequencer and upgrading of a confocal microscopy system; and (4) funding for collaborative pilot research projects to apply novel strategies to disease- and patient-oriented research in areas such as gene therapy in cancer, study of polymorphisms in genes of interest in human diseases, and functional genomics of microbes in infectious disease.
Tufts University School of Medicine
Boston, Massachusetts
$1.8 million over four years is being used to (1) support start-up packages for eight junior faculty in the areas of microbial pathogenesis, structural biology, and signal transduction; (2) purchase equipment for a structural biology core facility and subsidize junior faculty use of a macromolecular analysis core, a cell sorting core, and a transgenic core; and (3) provide bridge funding packages for three assistant professors in the fields of microbial pathogenesis, structural biology, and signal transduction.
University of Alabama School of Medicine
Birmingham, Alabama
$1.8 million over four years is being used to support (1) start-up packages for six junior faculty in the areas of genetics, signal transduction, and vaccine research and (2) salary and other support for a micro-sequence array technology (gene chip) shared facility.
University of California, Irvine, School of Medicine
Irvine, California
$2.2 million over four years is being used to (1) support start-up packages for five assistant professors in the areas of internal medicine, pediatrics, psychiatry, and biological chemistry; (2) provide equipment and salary support for a computing and informatics core facility and a gene mapping and expression core; and (3) provide equipment for a molecular structure virtual reality facility.
University of California, Los Angeles, UCLA School of Medicine
Los Angeles, California
$4 million over four years is being used to (1) support start-up packages for eight junior faculty in the areas of genomics, proteomics, or bioinformatics; (2) provide equipment for a transgenic mouse core facility and a new functional genomics core and support the expansion of an existing imaging facility into a bioinformatics core and expansion of a disease mapping core into a new human genomics core; and (3) fund 52 pilot research projects awarded through the Frontiers in Science program (genomics and bioinformatics) and the Specialty Training and Advanced Research program and Pediatric Research Innovation and Mentoring Experience program (the latter two for physician-scientists).
University of California, San Francisco, School of Medicine
San Francisco, California
$3.8 million over four years is being used to support expansion and reorganization of the school into two campusesÑone for basic science research (Mission Bay) and the other for disease-oriented research (Parnassus Heights)Ñthrough (1) start-up packages for 13 assistant professors; (2) equipment for a new genetics studies unit core facility; and (3) renovation and updating of laboratories.
University of Chicago Division of the Biological Sciences and Pritzker School of Medicine
Chicago, Illinois
$2.4 million over four years is being used to (1) support start-up packages for six assistant professors in the areas of immunology and structural biology; (2) provide equipment and salary support to enhance core facilities in crystallography and biophysical and macromolecular analysis, and establish a basic immunology and immunotherapy core; and (3) fund a program of seed grants to encourage innovative research in immunology and structural biology.
University of Cincinnati School of Medicine
Cincinnati, Ohio
$2 million over four years is being used to establish three interlinked core facilities for expression technology: a gene expression core for cDNA microarray creation and data generation, a proteomics core for the identification and characterization of protein molecules, and a bioinformatics core with computer systems for genome sequence database analysis.
University of Colorado School of Medicine
Denver, Colorado
$1.6 million over four years is being used to (1) support start-up packages for 10 junior faculty, about half working in the area of molecular structure and (2) provide equipment and salary support for a protein mass spectrometry and proteomics core facility, an X-ray crystallography core, and a computing and informatics core.
University of Florida College of Medicine
Gainesville, Florida
$1.8 million over four years is being used to (1) support start-up packages for eight assistant professors in the areas of functional genomics, gene delivery, animal models, immunogenetics, and gene mapping complex diseases; (2) provide equipment for the Center for Immunology and Transplantation, the Center for Gene Therapy, and the Center for Mammalian Genetics; (3) provide bridge funding to help junior faculty fund salaries of postdoctoral fellows; (4) provide contingency funds to maintain an assistant professor's research without interruption; (5) support a visiting scholars program to enable junior faculty to interact with highly regarded scientists; and (6) fund approximately 20 pilot projects for molecular genetics research.
University of Iowa College of Medicine
Iowa City, Iowa
$2.6 million over four years is being used to (1) provide start-up packages for eight junior faculty in the area of molecular medicine and molecular neuroscience; (2) purchase a mass spectrometer for a molecular analysis facility and upgrade the existing NMR for MRI in the NMR facility; and (3) support eight collaborative pilot research projects in molecular medicine and molecular neuroscience.
University of Massachusetts Medical School
Worcester, Massachusetts
$1.6 million over four years is being used to (1) support start-up packages for four junior faculty (one with expertise in high-field NMR and three with expertise in bioorganic and medicinal chemistry) to enhance the program in chemical biology and (2) provide equipment and salary support for a new chemistry core facility.
University of Michigan Medical School
Ann Arbor, Michigan
$4 million over four years is being used to (1) support start-up packages for four junior faculty to support the development of a bioinformatics program; (2) provide equipment and salary support for a new bioinformatics core facility; (3) support renovation of research and core facility space; and (4) fund a competitive program of pilot grants to foster collaboration between researchers in the biomedical and computational sciences.
University of Minnesota Medical School-Minneapolis
Minneapolis, Minnesota
$1.6 million over four years is being used to (1) provide start-up packages for four junior faculty, particularly physician scientists, in the fields of tumor immunotherapy and immunodiagnostics, transplantation, infectious diseases/AIDS, and autoimmunity/diabetes and (2) support expansion of a mouse genetics laboratory core facility to support these new faculty.
University of North Carolina at Chapel Hill School of Medicine
Chapel Hill, North Carolina
$2.6 million over four years is being used to (1) support start-up packages for four junior faculty, in the areas of mouse and human genetics, to staff a new department of genetics; (2) provide equipment and salary support to develop two new core facilities (a genomics core and a chromosome imaging core); and (3) fund pilot research projects, particularly those applying bioinformatics, that will use these cores to develop and study human and animal genetic models.
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
$2 million over four years is being used to support a new program in cognitive neuroscience by (1) supporting start-up packages for four junior faculty and (2) upgrading an existing MRI scanner in the functional MRI core facility and providing equipment and salary support for an image analysis core facility.
University of Rochester School of Medicine and Dentistry
Rochester, New York
$1.8 million over four years is being used to (1) provide start-up packages for four junior faculty, two in the Center for Cancer Biology and two in the Center for Vaccine Biology and Immunology; (2) defray operating expenses of core facilities and acquire a cell sorter and instrumentation for FRET microscopy analysis for the imaging core; and (3) support approximately 12 pilot projects emphasizing collaboration between basic research scientists and those conducting disease- or patient-oriented research.
University of Texas Medical Branch, University of Texas Medical School at Galveston
Galveston, Texas
$2 million over four years is being used to (1) provide start-up packages for four junior faculty in the fields of genomics/bioinformatics, molecular design, membrane-protein structural biology, and molecular immunology/virology and (2) provide equipment and salary support to establish a genomics/bioinformatics core facility, a membrane proteins core, and a drug design core.
University of Texas Medical School at San Antonio
San Antonio, Texas
$1.6 million over four years is being used to (1) provide start-up packages for junior faculty (three to five each year); (2) fund pilot projects, especially for junior faculty, emphasizing interdisciplinary research; and (3) fund an enrichment program to support visiting scientists, an annual conference, mini-sabbaticals, and supplements for trainees.
University of Texas Southwestern Medical Center at Dallas Southwestern Medical School
Dallas, Texas
$1.8 million over four years is being used to support start-up packages for four assistant professors, two in neuroscience and two in immunology.
University of Utah School of Medicine
Salt Lake City, Utah
$2.2 million over four years is being used to support start-up packages, awarded through the Fellowship-to-Faculty Transition program for physician scientists, for 10 to 12 junior faculty with research interests in cellular and molecular biology, cell signaling, genetics, neurobiology, vascular biology/inflammation, and cancer biology, with slots to be distributed among the clinical departments of pediatrics, internal medicine, neurology, dermatology, surgery, and reproductive medicine.
University of Vermont College of Medicine
Burlington, Vermont
$1.8 million over four years is being used to (1) provide start-up packages for two junior faculty (one with expertise in population-based studies, the other with expertise in cryo-electron microscopy research) and (2) support operating expenses and provide salary support for existing NMR, X-ray crystallography, and transgenic core facilities and provide equipment and salary support for a new cryoelectron microscopy core.
University of Wisconsin Medical School
Madison, Wisconsin
$1.6 million over four years is being used to (1) support start-up packages for 20 junior faculty, including physician-scientists, with expertise in molecular genetics, cell biology, and neuroscience and (2) fund pilot research projects in the areas of genetics, cell biology, and molecular neuroscience.
Washington University School of Medicine
St. Louis, Missouri
$2.4 million over four years is being used to (1) provide start-up packages for four assistant professors and (2) support four trainees—selected for a new faculty developments—clinical investigator programÑwho will enter as instructors and be ready for promotion to assistant professor by the end of the fourth year. Candidates will spend time with a senior investigator, take courses, and eventually transit to their own laboratories.
West Virginia University School of Medicine
Morgantown, West Virginia
$1.6 million over four years is being used to (1) support start-up packages for three junior faculty in the area of neuroscience; (2) provide equipment and salary support to establish a transgenic core facility; (3) support renovation of laboratories for the newly recruited junior faculty; and (4) fund a pilot team development grant to support interdisciplinary, collaborative research in neuroscience.
Yale University School of Medicine
New Haven, Connecticut
$4 million over four years is being used to support (1) start-up packages for six assistant professors working on the molecular genetic basis of human disease; (2) equipment for a DNA sequencing/genotyping core facility and for equipment and operating costs for a new macromolecular core facility that will focus on the production and reading of DNA microarrays; (3) minor renovations of laboratories in the department of genetics; and (4) pilot research projects on the molecular genetics of human disease.
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