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Hepatitis C Virus: A Global Pandemic Webcasts
In a series of five webcasts, experts from the University of Washington and two other institutions offer a complete, up-to-the-minute picture of the Hepatitis C virus. This virus—for which no vaccine exists—can cause a chronic infection that is a major cause of cirrhosis and liver cancer worldwide. In her opening talk, “The Epidemiology and Natural History of the Hepatitis C Virus Infection,” Miriam Alter, Ph.D., offers a broad overview that discusses the appearance and spread of Hepatitis C. In “The Molecular Virology of Hepatitis C,” Stephen Polyak, Ph.D., explains how the Hepatitis C virus interacts with the host and causes disease. In the third talk, “The Hepatitis C Virus and Hepatocellular Carcinoma,” Stanley Lemon, M.D., describes what is known about the mechanisms by which a Hepatitis C infection can become cancer in the liver. The fourth talk, “Hepatitis C Infection and Immunity,” given by Michael Gale, Ph.D., explains the interactions between the Hepatitis C virus and the immune system. In the last talk, “Current and Future Treatment of Chronic Hepatitis C,” John D. Scott, M.D., describes available treatment options, as well as approaches in development. Although the talks can be viewed singly, they were created as part of a course entitled “Challenges in Molecular Medicine,” so showing them in order might help students better understand the science and medicine involved in this complex disease.
The Lifecycle of the Hepatitis C Virus
Five webcasts, with slides, paint a current picture of the intricacies of the Hepatitis C virus. The slide above, from the "Molecular Virology" webcast, shows the lifecycle of the virus.
Media: Flash MultimediaProgram Director: Nancy Maizels, Ph.D.
Award Years: 2006
Summary: The University of Washington is a public research university in Seattle, Washington. Its Molecular Medicine Training Program, funded by HHMI's Med into Grad Program, provides Ph.D. students with training that integrates fundamental principles of biology with human health and disease. The program incorporates three key elements: case-based courses, a clinical rotation in human genetics or a medical pathology course, and dual mentorship of Ph.D. research by a basic scientist and a clinically trained or clinically oriented research scientist.