Myosin

Myosin is best known for its role in muscle contraction, but it also lends power to a variety of other processes such as vesicle and organelle transport. Unlike kinesin and dynein, which travel on microtubules, myosin trucks along on actin filaments. The motor’s two head domains bind to actin and use ATP to generate motion while its tail binds to cargo or other myosin molecules. In muscle cells, the long coiled tails of the individual myosin molecules join together, forming thick filaments.