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February 2012
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Rational Exuberance
A Structural Revolution
One Foot in Front of the Other
A Happy Oasis

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Letter from Bob Tjian
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Taking the Long View small arrow
In the life of an institute such as HHMI, there are exceptional events that hold particular significance.

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Perspectives & Opinions
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SYDNEY BRENNER:
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Taking inspiration from the best.

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Centrifuge
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Image Tethered to the Wind
From early spring until late fall, Nobel laureate Craig Mello kiteboards whenever the wind is right. Moresmall arrow
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Up Front
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Image Cellular Search Engine
Caenorhabditis elegans germ cells constantly scan their contents looking for unfamiliar genetic material. Moresmall arrow
Image Something’s Brewing
Making beer is half art and half science, so it’s the perfect diversion for researcher Jasper Akerboom. slideshow icon
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Image Sister Act
Peering inside an intact brain shows that related neurons work together. Moresmall arrow
Image Musical Magnet
Andrey Shaw doesn’t know why students with backgrounds in music gravitate to his lab.
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Image Rickety for a Reason
Researchers investigate a fragile but powerful enzyme in the cell membrane. web only Moresmall arrow
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Chronicle
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Science Education
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Image Trash Is Treasure
Landfill-bound materials take a detour to enliven classroom learning.
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Lab Book
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Image Melody-Modifying Mice
An unexpected brain connection reveals that mice can learn new features of their songs. slideshow icon Moresmall arrow
Image The Past, Present, and Future Earth
The 2012 Holiday Lectures on Science explores our changing planet. web only Moresmall arrow
Image Tunneling Out
Bulky RNA–protein particles take a surprising route through the nuclear membrane. video icon Moresmall arrow
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Image A Trick of Light
miniSOG, a protein label used in microscopy, can also trigger cell death on demand.
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Image A Time to Transcribe
In the mouse liver, almost all DNA transcription occurs at the same time every day. web only Moresmall arrow
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