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Summer '04
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A Wellspring of Scientists
A Mentor and Four Students
   

Microbiologist Mary M. Allen works with Wellesley College undergraduates unraveling the mysteries of cyanobacteria, perhaps the oldest oxygen-producing organisms on earth. "There's no middleman in our laboratories—no postdocs or graduate students between me and my students," says Allen. For decades, Wellesley has produced more scientists than all but a handful of other liberal arts colleges.

When Allen joined the Wellesley faculty in 1968, she marveled at how much time colleagues spent with undergraduates. "I thought I had died and gone to heaven. It was just fantastic," she recalls.

The faculty-student collaboration process at Wellesley requires patience. "The undergraduates take three years to do what a postdoc probably could do in a year, but the quality is the same," says Allen, a past president of the Council on Undergraduate Research. Three of her students became Beckman Scholars—recipients of $17,600 scholarships from the Arnold and Mabel Beckman Foundation for research over two summers and the senior year. In interviews, three Wellesley graduates and a senior spoke about their mentor.

Keren Lisa Witkin '98 graduated this spring from UC Berkeley with a Ph.D. in molecular and cell biology. She didn't envision a career in science when she entered Wellesley, "but in my first year I took 'Intro to Cell Biology' and loved it." The summers in Allen's lab were "a lot of fun," Witkin recalls. "We were a tight group. Mary was always encouraging." She calls Allen "a phenomenal mentor."

Witkin wrote her undergraduate thesis on heat-shock response in cyanobacteria, and she and Allen presented a poster on that work at the VI Cyanobacterial Workshop in Pacific Grove, California, in July 1998.

"That was one of the best parts about doing research as an undergraduate," Witkin says. "It was very unusual to go to meetings with undergraduates. Mary took two of us. We got to present our research in front of all these real scientists. The experience was amazing."

Jean Jing Huang '01 arrived at Wellesley knowing she wanted to study biology. "I had great mentors in a public elementary school in Brookline, Massachusetts. A friend and I won the science fair in sixth grade," she says. "We developed a test for lead in paint, and we went around town testing the paint in the library and other places."

Huang worked in Allen's lab during the summer after freshman year, looking at acid shock. Allen "was there when I needed help, but she wasn't telling me what to do. That was the best part, because I developed confidence," says Huang. The students even had keys to the lab, allowing them to work with a buddy late at night and on weekends.

"This project was very forgiving," she says. "I tried a lot of experiments. I'd take a course and learn about some technique, then try it with the cyanobacteria. Since we weren't looking for any one result, it could develop in all these different, interesting ways. We used NMR [nuclear magnetic resonance] spectrometers and all sorts of instruments, and we collaborated with other labs on campus." Huang, who became Allen's first Beckman Scholar, wound up presenting a paper at a microbiology conference in Barcelona and was the lead author of a paper published in the Archives of Microbiology.

"I really saw the best of what science was all about at Wellesley," says Huang, a third-year graduate student in biology at the California Institute of Technology. "The only model I saw was a successful professor." [HHMI, recognizing that graduate students and postdoctoral fellows may also serve as mentors, supports programs that train them in teaching as well as research at both colleges and universities.]

 
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Is this heaven? When Mary Allen joined the Wellesley faculty, she marveled at how much time colleagues spent with undergraduates.


Return to "A Wellspring of Scientists"

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  SMALL COLLEGES MAKE
BIG INVESTMENTS

Infrastructure and facuty
provide the environment for
science to prosper.
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SELECT BACCALAUREATE INSTITUTIONS ARE TOP PRODUCERS
The top 25 baccalaureate
institutions are very productive.
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A MENTOR AND
FOUR STUDENTS

There is no "middleman" in the science labs at Wellesley.
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THE FACULTY'S
GREATEST PASSION

At Swarthmore, the road to a
Ph.D. starts in Bio 1 and 2.
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STRIVING TO SUCCEED
Traditionally minority and
majority colleges alike offer benefits to students, and faculty, of color.
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EXPECT THE UNEXPECTED
An eminent investigator's perspectives on the best preparation for a life in science.
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RIGHT WHERE
THEY BELONG

Combining the pleasures of teaching and research at small liberal arts colleges.
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COLLABORATION IN THE
NAME OF SCIENCE

A college-university alliance proves to be a win-win-win.
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HHMI AND LIBERAL
ARTS SCIENCE

$600 million in support of undergraduate science education.
 
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Katie Shea '03 was bursting to do science, thanks in part to mentoring from her high school biology teacher, when she arrived at Wellesley from rural New Hampshire. She became Allen's second Beckman Scholar. (The third, Sogole Moin, class of 2005, received the honor just this spring.)

Allen "had an open-door policy. If things weren't going right, you'd ask her questions. She was floating in and out of the lab all the time," says Shea. Allen and other professors also met jointly each week with the students working in their labs, sharing progress reports and offering suggestions on how to deal with bottlenecks.

Shea took up the acid-stress work in her junior year, presented posters at American Society of Microbiology meetings in Salt Lake City and Washington, D.C., and graduated summa cum laude. She is now at Dartmouth Medical School, with her cap set toward pediatric oncology.

"I definitely want research to be part of my career," says Shea. "That's one aspect of oncology—your research can coordinate well with your clinical skills."

Tam-Linh N. Nguyen '04 came to Wellesley from Pennsylvania as a pre-med major, but soon switched to biology. When the opportunity came to work in Mary Allen's lab, Nguyen embraced it. "I found that I really, really liked being in the lab, I liked working with instruments, I liked doing science," she says.

Nguyen picked up the acid-stress work where Katie Shea left off. "They've already done so much work on this, I am a successor," she says. "But I feel like I'm contributing something to their project." If things fall into place, eventually a paper will be published with all the participants' names on it.

The young researcher says "Professor Allen is so approachable and so down-to-earth, she doesn't intimidate any of the students. I can talk with her about my problems. I talk to her about all sorts of things." They even discuss the progress of her sister Michelle, who just finished her freshman year at Wellesley.

Perhaps Allen has an eye on Michelle for the lab, too? "Possibly—or my sister has an eye on her," Nguyen replies. "If you want a mentoring relationship like that, you can't just sit around waiting for it to come to you. You have to go out and find it."

—Christopher Connell

Photo: Jason Grow

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Reprinted from the HHMI Bulletin,
Summer 2004, pages 10-21.
©2004 Howard Hughes Medical Institute

 
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