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January '01
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Dr. Steitz's
HHMI Research
Abstract

Dr. Steitz's
Laboratory
Home Page at
Yale University
Building a Blueprint of the Cell's Protein Factory

 

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Caught in the Act

 

 3-D Tracking of Changes in Ribosome Structure and Shape

 

 

 

 Luring Recruits

 

 Getting students interested in big molecules early

 

 

 

 
   
       
 
 

If the genome is the blueprint that defines an organism and directs every facet of its operation, then the ribosome is where the bare-knuckled work of carrying out those instructions takes place. A typical human cell contains millions of these protein-building factories, where the 20 different amino acids derived from foods are linked together—one at a time, accurately and rapidly—into the proteins needed for life.
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Photo: Harold Shapiro

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Reprinted from the HHMI Bulletin,
January 2001, pages 12-17.
©2001 Howard Hughes Medical Institute

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