HHMI Bulletin November 2009


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The Most Vulnerable Patients






	Fall may be the “season of mists and mellow fruitfulness,” as English Romantic poet John Keats described it nearly two centuries ago.






	TERRY SEJNOWSKI: If you think it's bad, think again.

	CHARLES SAWYERS: It may soon be possible to determine—and arrest—the driver of each patient's cancer.

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	From the Outside Looking In On a train from Switzerland to Italy, in March 2008, Mirko Bischofberger came up with an idea for a website. More		Where Past Meets Future Over three decades, Winston Anderson filled his garage with objects and documents tracing the history of African slaves and their American descendants. More		Leapin' Lizards Navigating the Grand Staircase-Escalante National Monument in southern Utah involves... More






	Piecing Together Rotavirus's Unique Approach An extra protective layer primes this virus to do its harm, mainly in children in the developing world. More		Seeing Spots Relying on old-fashioned techniques allowed these researchers to make a surprising discovery. More		Dangerous Agent A model bacterium is showing scientists how pathogens go from harmless to deadly. More




	Rummaging for Science Sometimes everyday objects make the best teaching tools in the classroom. More		2009 Holiday Lectures: Exploring Biodiversity Sometimes it pays to look in unlikely places to uncover the secrets of biology. More

	Removing Radiation Roadblock Researchers have found the protein that makes some tumors unresponsive to radiation. More		Starving for GABA A small chemical in the brain is the difference between eating and wasting away. More		Blue Baby Blues A congenital heart defect is explained by new genetic clues. More

	Freeze Frame Cryo-EM is a way to view protein structures—now at atomic resolution—as they do their thing in the biological world. More

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