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In 1982, Stanley Prusiner, a biochemist at the University of
California, San Francisco (UCSF), isolated the first prion as
the cause of lethal scrapie in sheep. In 1997, he won a Nobel
Prize for the achievement and for characterizing a mechanism
for protein aggregation and self-perpetuation, or as the Nobel
committee wrote, “for his discovery of prions, a new biological
principle of infection.”
Illustration: Deth P. Sun
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