HHMI Bulletin May 2008


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Teaching Young Biologists New Tricks






	Even the damp, gray days so pervasive this spring can't diminish the extraordinary magic with which the season unfurls outside my office here at HHMI's headquarters in Maryland.






	Drug discovery is an expensive process that can take dozens of years and result in only a few compounds making it to market.

	Do biologists need to know how to build corrugated metal roofs?

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	Men Overboard This past summer, Rod MacKinnon and Clay Armstrong were reminded of a fundamental fact about the sea. More		The Sweet Smell of Exhaust "I've been around sports cars and racing cars for as long as I've been around science," says neurologist Peter St George-Hyslop. More		A Baroque Biochemist On Tuesday and Friday evenings, biochemist Alexander Konstantinov walks away from his spectrophotometer and picks up a different fine-tuned instrument. More






	Know When to Fold 'Em When the cell's protein-folding machinery is stressed, timing is everything in the decision to keep going or die. More		Freeze-Framing a Fidgety Molecule A sister-brother team conspires to pin down the ultrafast movements of enzymes in action. More		Baring HIV's Dependencies New atlas reveals that HIV commandeers almost 300 human proteins to do its dirty work. More





	Cue the Crickets An international collaboration among teen researchers goes chirpingly. More		Strategizing to Diversify Science Educational institutions share experiences, and agree to continue the collaboration, in attracting underrepresented minorities to science and retaining them.More		Hearing Through the Din Receptors embedded in the ear's hair cells might explain mammals' selective hearing. More

	In Memoriam: Richard G. Darman Richard Gordon Darman, a financial executive with a distinguished career in public service and a Trustee of the Howard Hughes Medical Institute, died January 25, 2008, in Washington, D.C. He was 64. More		HHMI Offers Boost to Early Career Scientists Many early career scientists launch their own labs with start-up funds from their host institution. More

	Of Fish and Men The same gene drives skin color evolution in stickleback fish and humans. More		Fixing Fragile X Knocking out a single gene in neurons eliminates symptoms of fragile X syndrome in mice. More		A New Clarity Applying a new microscopy technique to detect individual molecules in three dimensions. More

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