Small protein segments created by HHMI investigator Stanley J. Korsmeyer, Anthony Letai and their colleagues at the Dana-Farber Cancer Institute and Harvard Medical School have revealed important new details about the intricate machinery of cell suicide. The work, reported in the September 2002 issue of Cancer Cell, reveals two distinct pathways to trigger cell death and points the way to drugs that stimulate the process in cancer cells. continued...

Photo Illustration: Eric Smith/Korsmeyer Lab

Download this story in Acrobat PDF format.
(requires Acrobat Reader)

Reprinted from the HHMI Bulletin,
March 2003, pages 38–39.
©2003 Howard Hughes Medical Institute