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Fall '04
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See full illustration of the "Mechanisms of DNA Repair"
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Early Research
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Like begets like. Dogs never give birth to cats, and apple trees won't sprout from acorns. That is life's central dogma, arising from the dependable passage of DNA intact and in the same order from one cellular generation to the next. However, tens of thousands of times a day, the DNA in virtually every cell in every living organism, including humans, suffers genetic damage, chemically induced mutations, and simple mix-ups of one form or another. continued...

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Reprinted from the HHMI Bulletin,
Fall 2004, pages 50-54.
©2004 Howard Hughes Medical Institute
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