HHMI Investigator Karolin Luger is being honored by the Vilcek Foundation for her research into nucleosomes — the DNA-packaging structures inside cells — that has led to the development of innovative drugs for treating diseases, including cancer. By studying zebra finches as they sing, Freeman Hrabowski Scholar Vikram Gadagkar is uncovering how the brain learns, evaluates mistakes, and performs under pressure.HHMI Janelia Research Campus Group Leaders Alison Tebo and Srinivas Turaga are creating new AI models to optimize the development of sensors used to track biological processes happening inside cells in real time – key tools used to understand how the body and brain work.HHMI Investigator Kevan Shokat and his lab are charting new therapies to outmaneuver drug resistance and better target common cancer cell mutations.A team of researchers led by HHMI Investigator Michael Rosen has captured the most detailed images yet of the molecules in chromatin condensates — droplet-like structures of compacted DNA. HHMI scientists Michael Yartsev and Gerald Carter are uncovering how bats learn, remember, and form social bonds — findings that could reshape how we understand our own brains and behaviors.New research led by HHMI Janelia Research Campus Senior Group Leader Meng Wang provides insights into how changes that help organisms deal with environmental stress are conferred to their offspring. New research led by HHMI Investigator Vamsi Mootha and Fumito Ichinose shows that breathing low-oxygen air slows the progression of Parkinson’s disease in a laboratory model, raising the possibility of a new paradigm for addressing the disease that affects more than 10 million people worldwide. A team led by HHMI Investigator David Liu used prime editing — a precise and versatile form of gene editing — to correct the root cause of a rare and severe neurological disorder in a laboratory model. The new research suggests a potential path to treating the disease that currently has no cure or effective treatment. HHMI Investigator Chenghua Gu and her lab use innovative techniques to determine how blood flow to the brain is controlled in real time.