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Teacher Guide: Math and Statistics

Summary

Topics include measures of average (mean, median, and mode), variability (range and standard deviation), uncertainty (standard error and 95% confidence interval), Chi-square analysis, student t-test, Hardy-Weinberg equation, frequency calculations, and more. 

Many state science standards encourage the use of mathematics and statistics in biology education, including the newly designed AP Biology course, IB Biology, Next Generation Science Standards, and the Common Core. This guide was conceived to help biology teachers implement math and statistics in the classroom. It is not meant to be a textbook of statistics; it covers topics most relevant to high school biology, focusing on methods and examples rather than theory. The document also includes a chart of activities on the BioInteractive website that use several of the math and statistics methods covered in this guide.

A first draft of the guide was published in July 2014. It was revised on January 2015 based on user feedback and expert review, and with links to additional BioInteractive resources. Subsequent versions of the guide will include the ANOVA test and guidelines for using spreadsheet programs to calculate statistics and graph data.

Supporting Materials (7)

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Topics include: Gene regulation mechanisms and examples, gene regulation and human disease, and RNA interference.
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Topics include: Immunology, HIV immune response and drug development, ELISA, CCR5 co-receptor mutation, vaccine development, dengue fever, and immunological response
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Topics include: Gene expression, RNA structure and function, transcription, RNA processing, translation, and post-translational events.
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Topics include: natural selection, artificial selection, population genetics, human adaptations and evolution, and phylogenetics.
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Topics include: PCR, DNA Sequencing, Genetic Engineering, and Microarray. This guide includes multiple classroom-ready worksheets to accompany HHMI’s virtual labs.
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Topics include: DNA structure and function, DNA replication, damage to DNA and eukaryotic chromosomal structure.
Classroom Resource
This guide correlates all the resources available on the Holiday Lectures on Science DVDs and throughout the BioInteractive.org website to specific Big Ideas, Enduring Understandings, and Essential Knowledge threads of the new AP® Biology Curriculum Framework. 

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