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Showing 1-41 of 41 Resources
  • Stalking the Genetic Basis of a Trait

    Stalking the Genetic Basis of a Trait

    Activity

    In this activity students analyze data on the expression of the tb1 gene and use it to formulate an explanation as to how a specific difference in the corn version of the gene explains the phenotype of less branching.

  • Central Dogma and Genetic Medicine

    Central Dogma and Genetic Medicine

    Click & Learn

    This interactive uses the central dogma as a model for exploring how modern molecular biology technologies can be used to treat genetic diseases.

  • Top Notch Model Organism

    Top Notch Model Organism

    Image of the Week

    Close-up of cells in a fruit fly eye at the pupal stage stained with antibodies to the Notch protein.

  • Teacher Guides

    Teacher Guides

    Collection

    Designed by educators, BioInteractive’s teacher guides will help you select BioInteractive resources aligned to specific topics and standards, including the AP® Biology Curriculum Framework.

  • Designer Proteins

    Designer Proteins

    Image of the Week

    Scientists are custom-designing proteins, like these nanocages with many green fluorescent proteins attached

  • Genetically Modified Mosquitoes

    Genetically Modified Mosquitoes

    Scientists at Work

    (8 min 35 sec) Learn the process by which a line of genetically modified mosquitoes was engineered to reduce populations of Aedes aegypti mosquitoes in the wild.

  • Teeth of the Skin

    Teeth of the Skin

    Image of the Week

    The head of a newly-hatched catshark (Scyliorhinus canicula) imaged using 3D X-ray microscopy.

  • Understanding Variation

    Understanding Variation

    Activity

    This lesson complements the film The Biology of Skin Color and discusses variation in human skin color and polygenic inheritance. Also available in Spanish.

  • Zebrafish and Skin Color

    Zebrafish and Skin Color

    Activity

    This lesson complements the film The Biology of Skin Color and explores how experimental work in zebrafish led to a better understanding of the role of the gene SLC24A5 in human skin color.

  • Stickleback Film with Quiz

    Stickleback Film with Quiz

    Interactive Video

    (15 min 27 sec) Embedded quiz modules test students’ understanding as they watch a short film that explains how stickleback fish let scientists study evolution in action, identify key genes, and peer deep into the evolutionary past.

  • Lactase Film with Quiz

    Lactase Film with Quiz

    Interactive Video

    (14 min 52 sec) Embedded quiz modules test students’ understanding as they watch a short film that explores the evolution of the ability to digest lactose as adults (lactose tolerance) and the genetic changes associated with the trait.

  • Skin Color Interactive Video

    Skin Color Interactive Video

    Interactive Video

    (18 min 58 sec) Embedded quiz modules test students’ understanding as they watch a short film that explores the evidence for the evolution of the variation in skin color among human populations.

  • Genetic Origin of Variation in Human Skin Color

    Genetic Origin of Variation in Human Skin Color

    Data Point

    Dr. Rebecca Lamason and colleagues studied the genetic origin of variation in human skin color using a model organism, the zebrafish.

  • Film Guide for The Biology of Skin Color

    Film Guide for The Biology of Skin Color

    Film Guide

    The following classroom-ready resources complement The Biology of Skin Color. Featuring anthropologist Dr. Nina Jablonski, the film walks us through the evidence that differences in human skin color are adaptations to varying intensity of UV light. Also available in Spanish.

  • Lactase Persistence: Evidence for Selection

    Lactase Persistence: Evidence for Selection

    Activity

    This activity provides a case study in human evolution that connects genotype, phenotype, culture, and graphical analysis skills. Also available in Spanish.

  • How We Get Our Skin Color

    How We Get Our Skin Color

    Animation

    (3 min 32 sec) This engaging animation shows how human skin cells produce the pigment melanin, which gives skin its color. 

  • The Biology of Skin Color

    The Biology of Skin Color

    Short Film

    (18 min 58 sec) Penn State University anthropologist Dr. Nina Jablonski walks us through the evidence that the different shades of skin color among human populations arose as adaptations to the intensity of ultraviolet radiation in different parts of the world. Also available in Spanish.

  • Ocean Species Respond to Climate Change

    Ocean Species Respond to Climate Change

    Lecture

    (29 min 39 sec) Coral reefs, how they are threatened by climate change, and how to protect them.

  • Perfect Daughters

    Perfect Daughters

    Image of the Week

    Chromosomes change form as a cell divides to ensure that each daughter cell gets a full, intact copy of the genome.

  • Teacher Guide: Gene Expression

    Teacher Guide: Gene Expression

    Teacher Guide

    Topics include: Gene expression, RNA structure and function, transcription, RNA processing, translation, and post-translational events.

  • The Making of the Fittest: Got Lactase? The Co-evolution of Genes and Culture

    The Making of the Fittest: Got Lactase? The Co-evolution of Genes and Culture

    Short Film

    (14 min 52 sec) Follow human geneticist Spencer Wells, Director of the Genographic Project of the National Geographic Society, as he tracks down the genetic changes associated with the ability to digest lactose as adults. Also available in Spanish.

  • Film Guides: Evolving Switches, Evolving Bodies

    Film Guides: Evolving Switches, Evolving Bodies

    Film Guide

    These classroom-ready resources complement the short film Evolving Switches, Evolving Bodies, which tells the story of the dramatic transformation of stickleback fish as they adapted to living in freshwater habitats drastically different from the ocean.

  • The Making of the Fittest: Evolving Switches, Evolving Bodies

    The Making of the Fittest: Evolving Switches, Evolving Bodies

    Short Film

    (15 min 27 sec) After the end of the last ice age 10,000 years ago, populations of marine stickleback fish became stranded in freshwater lakes dotted throughout the Northern Hemisphere in places like Alaska and British Columbia. These fish have adapted to a freshwater environment drastically different than the ocean.

  • Regulation of the Lactase Gene

    Regulation of the Lactase Gene

    Click & Learn

    Lactase persistence results from a mutation that changes how transcription factors interact, thereby affecting gene expression.

  • The Molecular Evolution of Gene Birth and Death

    The Molecular Evolution of Gene Birth and Death

    Activity

    An advanced lesson that describes the role of mutations in the birth and death of genes. It includes background information, examples, video clips, and animations.

  • Molecular Genetics of Color Mutations in Rock Pocket Mice

    Molecular Genetics of Color Mutations in Rock Pocket Mice

    Activity

    A lesson that requires students to transcribe and translate portions of the wild-type and mutant rock pocket mouse Mc1r genes and compare sequences to identify the locations and types of mutations responsible for the coat color variation described in the film. Also available in Spanish.

  • The Central Dogma Song

    The Central Dogma Song

    Clip

    (5 min 55 sec) “The Assemblers” (Peter Skewes-Cox and Dr. Graham Ruby) sing about DNA and proteins.

  • Dengue Virus Life Cycle

    Dengue Virus Life Cycle

    Animation

    (4 min 12 sec) Dengue virus has sophisticated mechanisms for entering a cell, for replicating its RNA genome, and for translating proteins.

  • HIV life cycle

    HIV life cycle

    Animation

    (4 min 52 sec) How HIV infects a cell and replicates itself using reverse transcriptase and the host's cellular machinery.

  • Protease inhibitors

    Protease inhibitors

    Animation

    (1 min 6 sec) Protease inhibitors prevent maturation of viral proteins inside HIV particles.

  • Understanding Embryonic Stem Cells

    Understanding Embryonic Stem Cells

    Lecture

    (58 min 27 sec) An overview of embryonic development, the progressive differentiation of cells, and properties of embryonic stem cells.

  • Visualizing Gene-Expression Patterns

    Visualizing Gene-Expression Patterns

    Click & Learn

    Learn about the different ways scientists are able to detect when genes are being expressed in various tissues.

  • Translation (basic detail)

    Translation (basic detail)

    Animation

    (2 min 6 sec) The ribosome is a molecular factory that translates the genetic information in RNA into a string of amino acids that becomes a protein. Inside the ribosome, the genetic code of the RNA is read three letters at a time and compared with the corresponding code on a transfer molecule. When a match occurs between the codes, the amino acid carried by the transfer molecule is added to the growing protein chain. Also available in Spanish.

  • Sex and Death: Too Much of a Good Thing

    Sex and Death: Too Much of a Good Thing

    Lecture

    (59 min 6 sec) Having too many chromosomes can lead to too much gene expression. Dr. Meyer explains how the gene that controls dosage compensation in C. elegans works.

  • Hermaphrodites: The Safer Sex

    Hermaphrodites: The Safer Sex

    Lecture

    (56 min 32 sec) Dr. Barbara Meyer explains the value of studying model organisms and introduces the nematode C. elegans.

  • The Mammalian Timekeeper

    The Mammalian Timekeeper

    Lecture

    (57 min 50 sec) Dr. Takahashi describes the powerful strategies that he and others have harnessed for understanding biological clocks in mammals.

  • PERfect TIMing

    PERfect TIMing

    Lecture

    (57 min 32 sec) Dr. Rosbash discloses how scientists have persuaded Mother Nature to reveal the inner workings of the fruit fly's biological clock.

  • Unwinding Clock Genetics

    Unwinding Clock Genetics

    Lecture

    (56 min 42 sec) Although tiny in size, the fruit fly has had a major impact on our understanding of circadian rhythms.

  • Clockwork Genes: Discoveries in Biological Time

    Clockwork Genes: Discoveries in Biological Time

    Lecture

    Four lectures highlight the research of two scientists who have made groundbreaking discoveries elucidating the molecular basis of circadian clocks—the internal timekeepers that govern fluctuations in behavior and physiology on a 24-hour cycle.

  • How Immune Cells Create Trillions of Receptors from a Few Hundred Parts

    How Immune Cells Create Trillions of Receptors from a Few Hundred Parts

    Lecture

    (59 min 48 sec) The human body has at least a trillion ways of recognizing that something foreign has invaded.

  • The Double Life of RNA

    The Double Life of RNA

    Lecture

    In four lectures, Nobel laureate Thomas R. Cech, PhD, discusses the ability of RNA to act as more than just an intermediary between DNA and proteins.

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