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Showing 101-115 of 115 Resources
  • Transgenic Fly Virtual Lab

    Transgenic Fly Virtual Lab

    Virtual Lab

    The lab will familiarize you with the science and techniques used to make transgenic flies to study circadian rhythms.

  • The Mammalian Timekeeper

    The Mammalian Timekeeper

    Lecture

    (57 min 50 sec) Dr. Takahashi describes the powerful strategies that he and others have harnessed for understanding biological clocks in mammals.

  • PERfect TIMing

    PERfect TIMing

    Lecture

    (57 min 32 sec) Dr. Rosbash discloses how scientists have persuaded Mother Nature to reveal the inner workings of the fruit fly's biological clock.

  • Unwinding Clock Genetics

    Unwinding Clock Genetics

    Lecture

    (56 min 42 sec) Although tiny in size, the fruit fly has had a major impact on our understanding of circadian rhythms.

  • Biology in Four Dimensions

    Biology in Four Dimensions

    Lecture

    (58 min 12 sec) Dr. Joseph Takahashi takes us on an exciting journey into a very special region of the brain—the biological clock that governs our physiology and certain behaviors.

  • Clockwork Genes: Discoveries in Biological Time

    Clockwork Genes: Discoveries in Biological Time

    Lecture

    Four lectures highlight the research of two scientists who have made groundbreaking discoveries elucidating the molecular basis of circadian clocks—the internal timekeepers that govern fluctuations in behavior and physiology on a 24-hour cycle.

  • Mouse Circadian Activity

    Mouse Circadian Activity

    Clip

    (42 sec) This time-lapse videoclip illustrates a mouse's nocturnal behavior.

  • Human Circadian Activity

    Human Circadian Activity

    Clip

    (48 sec) This time-lapse videoclip shows human circadian activity while assembling a T. rex skeleton.

  • Interview with Dr. Joseph Takahashi

    Interview with Dr. Joseph Takahashi

    Interview

    (6 min 12 sec) A brief interview with Dr. Takahashi.

  • Interview with Dr. Ron Konopka

    Interview with Dr. Ron Konopka

    Interview

    (44 sec) Dr. Benzer is joined by Dr. Ron Konopka for a brief discussion of how the per gene is involved in mammalian clocks.

  • Interview with Dr. Seymour Benzer

    Interview with Dr. Seymour Benzer

    Interview

    (57 sec) Are you a night owl or a morning lark? Noted researcher Dr. Seymour Benzer discusses how the difference between he and his wife sparked his interest in the topic of biological clocks.

  • The Drosophila Molecular Clock Model

    The Drosophila Molecular Clock Model

    Animation

    (7 min 35 sec) Watch these animations display the dynamic orchestration of the molecular events of the Drosophila biological clock.

  • Measuring Circadian Activity in Drosophila

    Measuring Circadian Activity in Drosophila

    Animation

    (2 min 3 sec) This animation series shows four experiments that compare the activity patterns of a wild-type fly keeping a normal schedule with those of a mutant fly apparently following a 19-hour internal clock.

  • The Mammalian Molecular Clock Model

    The Mammalian Molecular Clock Model

    Animation

    (3 min 41 sec) This animation shows the molecular interactions involved in the negative feedback loop responsible for circadian rhythms in mammals.

  • The Human Suprachiasmatic Nucleus

    The Human Suprachiasmatic Nucleus

    Animation

    (1 min 41 sec) In mammals, the controlling clock component that generates a 24-hour rhythm is the suprachiasmatic nucleus (SCN), located in a part of the brain called the hypothalamus. The SCN produces a signal that can keep the rest of the body on an approximately 24-hour schedule. This animation illustrates the location of the SCN in the human brain.

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