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  • Dengue Virus Life Cycle

    Dengue Virus Life Cycle

    Animation

    (4 min 12 sec) Dengue virus has sophisticated mechanisms for entering a cell, for replicating its RNA genome, and for translating proteins.

  • Viral Geometry and Structural Diversity

    Viral Geometry and Structural Diversity

    Animation

    The geometric structures of viruses are beautiful and can be used, along with genomic information, to identify them.

  • HIV Life Cycle and Drug Targets

    HIV Life Cycle and Drug Targets

    Poster

    The poster from the 2007 Holiday Lectures on Science, AIDS: Evolution of an Epidemic. It shows each stage of the HIV life cycle and highlights points in the cycle that have been targeted by anti-retroviral drugs.

  • Drug Adherence and Resistance

    Drug Adherence and Resistance

    Click & Learn

    Problems associated with adherence to antiviral drugs, and a student activity that mimics adherence to a multi-drug regimen.

  • Retroviruses and Viral Diversity

    Retroviruses and Viral Diversity

    Click & Learn

    A brief discussion of what makes a virus a retrovirus, and how they differ from other types of viruses.

  • Students Fighting the HIV Epidemic

    Students Fighting the HIV Epidemic

    Lecture

    (1 hr 21 min 27 sec) A discussion with three students who are helping in the global fight against HIV and AIDS.

  • Drugs and HIV Evolution

    Drugs and HIV Evolution

    Lecture

    (58 min 29 sec) Treating HIV infection with antiretroviral therapy, and HIV's ability to develop drug resistance.

  • AIDS and the HIV Life Cycle

    AIDS and the HIV Life Cycle

    Lecture

    (58 min 29 sec) The HIV life cycle, and how the virus destroys the immune system's ability to respond to infection.

  • From Outbreak to Epidemic

    From Outbreak to Epidemic

    Lecture

    (58 min 29 sec) The genesis of AIDS, identifying HIV as the virus that causes AIDS, and the modern global epidemic.

  • AIDS: Evolution of an Epidemic

    AIDS: Evolution of an Epidemic

    Lecture

    Why has it been so hard to develop a vaccine against HIV? How are new medicines revolutionizing AIDS treatment? Can AIDS be cured?

  • Symptoms of acute HIV infection

    Symptoms of acute HIV infection

    Clip

    (57 sec) Adam Barrett remembers his symptoms of acute HIV infection.

  • HIV's origins in Africa

    HIV's origins in Africa

    Clip

    (1 min 11 sec) Dr. Beatrice Hahn discusses how HIV originated in Africa by cross-species transmission from chimpanzees to humans.

  • Origin of HIV

    Origin of HIV

    Clip

    (5 min 32 sec) Dr. Beatrice Hahn's research has traced the origin of HIV to chimpanzees in Cameroon.

  • Living with HIV

    Living with HIV

    Clip

    (4 min 47 sec) Catherine Gaynes, an HIV-positive patients, discusses her HIV diagnosis, how her family reacted, and avoiding HIV infection.

  • Benefits of an antiretroviral regimen

    Benefits of an antiretroviral regimen

    Clip

    (1 min 50 sec) Zinhle Thabethe describes how antiretroviral therapy has changed her life.

  • Adherence and resistance

    Adherence and resistance

    Clip

    (7 min 43 sec) Adam Barrett, a nurse who is HIV positive, discusses his first symptoms and the challenges of adhering to a drug regimen.

  • Adhering to an antiretroviral regimen

    Adhering to an antiretroviral regimen

    Clip

    (1 min 8 sec) Adam Barrett describes his seven-drug antiretroviral regimen and the importance of adherence.

  • HIV life cycle

    HIV life cycle

    Animation

    (4 min 52 sec) How HIV infects a cell and replicates itself using reverse transcriptase and the host's cellular machinery.

  • AZT blocks reverse transcriptase

    AZT blocks reverse transcriptase

    Animation

    (1 min 46 sec) HIV's reverse transcriptase mistakes AZT for thymidine. Once incorporated, AZT stops reverse transcription.

  • U.S. AIDS epidemic

    U.S. AIDS epidemic

    Animation

    A visual representation of the U.S. AIDS epidemic from 1981 to 1997. Each dot represents 30 cases.

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