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Showing 1-20 of 20 Resources
  • Seeing In the New Year

    Seeing In the New Year

    Image of the Week

    Multi-color labeling of photoreceptor neurons in the developing visual system of the fruit fly (Drosophila melanogaster).

  • Biological Basis of a Myth

    Biological Basis of a Myth

    Image of the Week

    Hydra is a small freshwater hydrozoan polyp that has the capacity to grow a new individual from any part of its body.

  • Zebrafish Brain Cells for Spontaneous Navigation

    Zebrafish Brain Cells for Spontaneous Navigation

    Image of the Week

    The brain and part of the spinal cord of a one-week-old zebrafish, showing neurons that are active during a left turn (green), a right turn (red), or when swimming straight ahead (blue)

  • Unconditional Love

    Unconditional Love

    Image of the Week

    A mother and her baby viewed using magnetic resonance imaging (MRI).

  • Dante's Story

    Dante's Story

    Clip

    (6 min 6 sec) Dante is a 10-year-old boy born with hemimegalencephaly—an enlargement of half his brain.

  • The Search for Genetic Mutations that Cause Autism

    The Search for Genetic Mutations that Cause Autism

    Clip

    (2 min 5 sec) Dr. Christopher Walsh discusses how genomic science has made enormous contributions to our understanding of the genetic causes of autism.

  • Meet Dante—A Young Boy with Hemimegalencephaly

    Meet Dante—A Young Boy with Hemimegalencephaly

    Clip

    (2 min 33 sec) Dante is a healthy 10-year-old boy who has had half his cerebral cortex surgically removed to treat his seizures.

  • Development of the Cerebral Cortex

    Development of the Cerebral Cortex

    Animation

    (1 min 43 sec) Most of the neurons of the cerebral cortex arise from progenitor cells that undergo repeated cell division.

  • Sizing Up the Brain Gene By Gene

    Sizing Up the Brain Gene By Gene

    Lecture

    (59 min 32 sec) Recent advances in DNA sequencing technology have led to a better understanding of the many genes that play a role in brain development.

  • Meet Chris Walsh

    Meet Chris Walsh

    Clip

    (2 min 3 sec) Dr. Walsh is an HHMI investigator whose research focuses on understanding the genes involved in the development and function of the human brain.

  • Genetic Mutations and Disease

    Genetic Mutations and Disease

    Poster

    The poster for the 2013 Holiday Lectures on Science, Medicine in the Genomic Era, illustrates the difference between germline and somatic cell mutations.

  • Building Brains: The Molecular Logic of Neural Circuits

    Building Brains: The Molecular Logic of Neural Circuits

    Lecture

    (58 min 29 sec) How a nerve cell gets its identity, sends axons, and makes connections with other cells.

  • Demo: SHH concentration and eye position

    Demo: SHH concentration and eye position

    Clip

    (1 min 22 sec) A reduction in the level of sonic hedgehog (SHH) gene expression can lead to cyclopia.

  • Long-distance neuronal path-finding

    Long-distance neuronal path-finding

    Clip

    (31 sec) Retinal axons travel across the brain, reading navigation cues, to find appropriate targets.

  • Growth cones in action

    Growth cones in action

    Clip

    (34 sec) The growth cones of two neurons sense and interact with one another.

  • Contact repulsion of a growth cone

    Contact repulsion of a growth cone

    Clip

    (1 min 5 sec) A growth cone contacts a repellant molecule on another axon, collapses, and withdraws.

  • Development of the human embryonic brain

    Development of the human embryonic brain

    Animation

    (1 min 40 sec) The fetal brain grows enormously during pregnancy, both in terms of its size and the number of neurons it has.

  • Repellant ephrin signals guide limb innervations

    Repellant ephrin signals guide limb innervations

    Animation

    (1 min 34 sec) The growth cone of a neuron avoids repellant molecules and navigates to innervate the appropriate muscle.

  • Signal molecules trigger transcription factors

    Signal molecules trigger transcription factors

    Animation

    (2 min 4 sec) Varying concentrations of a signaling molecule activate different transcription factors and determine cell fate.

  • Rett Syndrome

    Rett Syndrome

    Clip

    (2 min 52 sec) Dr. Zoghbi introduces the topic of Rett syndrome by showing how development usually progresses in a young girl. She then shows an excerpt from Silent Angels, introduced by Julia Roberts, which shows how Rett syndrome affects development.