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  • Identifying the Key Genes for Regeneration

    Identifying the Key Genes for Regeneration

    Scientists at Work

    (9 min 55 sec) Planarians have an amazing ability to regenerate lost tissues. In this video, scientists knock out two different genes in planaria to start to understand how the process works—and they generate animals with two heads and two tails!

  • The Heart of the Matter

    The Heart of the Matter

    Image of the Week

    Early theories of the heart’s role were largely based on its central position in the body.

  • The Embryo Puzzle

    The Embryo Puzzle

    Image of the Week

    A new technique tracks thousands of cells in the fruit fly (Drosophila) embryo during development.

  • Potent Stem Cells

    Potent Stem Cells

    Poster

    The poster from the 2006 Holiday Lectures on Science, Potent Biology: Stem Cells, Cloning, and Regeneration, illustrates the role of stem cells during human embryonic development.

  • Coaxing Embryonic Stem Cells

    Coaxing Embryonic Stem Cells

    Lecture

    (58 min 25 sec) In cloning, a cell's genetic machinery is reprogrammed. Can we similarly coax stem cells to become specific cell types?

  • Understanding Embryonic Stem Cells

    Understanding Embryonic Stem Cells

    Lecture

    (58 min 27 sec) An overview of embryonic development, the progressive differentiation of cells, and properties of embryonic stem cells.

  • Somatic Cell Nuclear Transfer Animation

    Somatic Cell Nuclear Transfer Animation

    Animation

    (52 sec) Somatic cell nuclear transfer (SCNT) is a technique for cloning. The nucleus is removed from a healthy egg. This egg becomes the host for a nucleus that is transplanted from another cell, such as a skin cell. The resulting embryo can be used to generate embryonic stem cells with a genetic match to the nucleus donor (therapeutic cloning), or can be implanted into a surrogate mother to create a cloned individual, such as Dolly the sheep (reproductive cloning).

  • Intracytoplasmic Sperm Injection (ICSI)

    Intracytoplasmic Sperm Injection (ICSI)

    Clip

    (1 min 16 sec) Video microscopy demonstrating how sperm from an infertile male can be injected into a female egg.