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  • Identifying the Key Genes for Regeneration

    Identifying the Key Genes for Regeneration

    Scientists at Work

    (9 min 55 sec) Planarians have an amazing ability to regenerate lost tissues. In this video, scientists knock out two different genes in planaria to start to understand how the process works—and they generate animals with two heads and two tails!

  • Signal molecules trigger transcription factors

    Signal molecules trigger transcription factors

    Animation

    (2 min 4 sec) Varying concentrations of a signaling molecule activate different transcription factors and determine cell fate.

  • Planarian Regeneration and Stem Cells

    Planarian Regeneration and Stem Cells

    Scientists at Work

    (11 min 47 sec) A mini-documentary discussing the remarkable regenerative capabilities of the planarian, and how HHMI researcher Alejandro Sánchez Alvarado uses them to study the biology of stem cells.

  • Rett Syndrome

    Rett Syndrome

    Clip

    (2 min 52 sec) Dr. Zoghbi introduces the topic of Rett syndrome by showing how development usually progresses in a young girl. She then shows an excerpt from Silent Angels, introduced by Julia Roberts, which shows how Rett syndrome affects development.

  • X Inactivation

    X Inactivation

    Animation

    (55 sec) This animation shows how the random deactivation of one of the X chromosomes in a pair can lead to a mozaicism in the expression genes. 

  • MIX-1

    MIX-1

    Animation

    (3 min 39 sec) This animation shows how MIX-1 facilitates both chromosome condensation and dosage compensation.